Preclinical Overview of Brinzolamide

The development of topically active carbonic anhydrase inhibitors (CAIs) is a significant recent achievement in glaucoma medical treatment. Brinzolamide, the newest topical CAI, exhibits selectivity, high affinity, and potent inhibitory activity for the carbonic anhydrase type II isozyme (CA-II), wh...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Survey of ophthalmology 2000, Vol.44, p.S119-S129
1. Verfasser:	DeSantis, Louis
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption AL-4862 Animals Blood Flow Velocity - drug effects brinzolamide carbonic anhydrase inhibition carbonic anhydrase inhibitor Carbonic Anhydrase Inhibitors - metabolism Carbonic Anhydrase Inhibitors - pharmacokinetics Carbonic Anhydrase Inhibitors - pharmacology Drug Evaluation, Preclinical Dutch-belted Eye - metabolism glaucoma Half-Life Humans Intraocular Pressure - drug effects intraocular pressure reduction ocular blood flow ocular comfort ocular hypertension Ophthalmic Solutions - pharmacokinetics Ophthalmic Solutions - pharmacology pigmented rabbit Rabbits Sulfonamides - metabolism Sulfonamides - pharmacokinetics Sulfonamides - pharmacology Thiazines - metabolism Thiazines - pharmacokinetics Thiazines - pharmacology thienothiazine sulfonamide Tissue Distribution topical
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!