A spontaneously arising porcine model of bullous pemphigoid

Bullous pemphigoid (BP) is an IgG-mediated autoimmune blistering disease targeting the hemidesmosomal proteins bullous pemphigoid antigens 1 and 2. Currently, there is no active animal model in which to dissect the immunopathogenic mechanism. We noticed that cutaneous blistering arose spontaneously...

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Veröffentlicht in:	Archives of Dermatological Research 2000-01, Vol.292 (1), p.37-45
Hauptverfasser:	OLIVRY, T, MIRSKY, M. L, SINGLETON, W, DUNSTON, S. M, BORRILLO, A. K. G, LUTING XU, TRACZYK, T, ROSOLIA, D. L, CHAN, L. S
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Autoantigens - analysis Biological and medical sciences Bullous diseases of the skin Carrier Proteins Collagen Collagen Type XVII Cytoskeletal Proteins Dermatology Disease Models, Animal Dystonin Enzyme-Linked Immunosorbent Assay Epitopes - analysis Fluorescent Antibody Technique Immunoblotting Immunosorbent Techniques Medical sciences Microscopy, Electron Microscopy, Fluorescence Microscopy, Immunoelectron Molecular Sequence Data Nerve Tissue Proteins Non-Fibrillar Collagens Pemphigoid, Bullous - immunology Pemphigoid, Bullous - metabolism Pemphigoid, Bullous - pathology Skin - chemistry Skin - pathology Skin - ultrastructure Swine Swine, Miniature
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