The Itinerary of a Vesicle Component, Aut7p/Cvt5p, Terminates in the Yeast Vacuole via the Autophagy/Cvt Pathways

Aminopeptidase I (API) is delivered to the yeast vacuole by one of two alternative pathways, cytoplasm to vacuole targeting (Cvt) or autophagy, depending on nutrient conditions. Genetic, morphological, and biochemical studies indicate that the two pathways share many of the same molecular components...

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Veröffentlicht in:	The Journal of biological chemistry 2000-02, Vol.275 (8), p.5845-5851
Hauptverfasser:	Huang, Wei-Pang, Scott, Sidney V., Kim, John, Klionsky, Daniel J.
Format:	Artikel
Sprache:	eng
Schlagworte:	aminopeptidase I aminopeptidases Aut7 protein Autophagy-Related Protein 8 Family Biological Transport - physiology Cell Membrane - chemistry Cloning, Molecular degradation Endopeptidases - metabolism Fungal Proteins - chemistry Fungal Proteins - genetics Fungal Proteins - physiology Kinetics Membrane Proteins - chemistry Microtubule-Associated Proteins - chemistry Microtubule-Associated Proteins - genetics Microtubule-Associated Proteins - physiology Mutation nitrogen Nitrogen - metabolism nutrient deficiencies Phagocytosis - physiology protein synthesis protein transport proteinases proteins proteolysis Saccharomyces cerevisiae Saccharomyces cerevisiae - chemistry Saccharomyces cerevisiae Proteins secretory granules Subcellular Fractions Time Factors vacuoles Vacuoles - chemistry zymogens
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