Identification of Epistatic Interactions Involved in Non-Insulin-Dependent Diabetes Mellitus in the Otsuka Long-Evans Tokushima Fatty Rat

The Otsuka Long-Evans Tokushima Fatty (OLETF) rat is an animal model for obese-type non-insulin-dependent diabetes mellitus (NIDDM) in humans. Our present investigation was designed to identify epistatic interactions influencing NIDDM by performing least squares analysis of variance of all pairs of...

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Veröffentlicht in:	Experimental Animals 2001, Vol.50(2), pp.115-123
Hauptverfasser:	YAMADA, Takahisa, MIYAKE, Takeshi, SUGIURA, Kenkichi, NARITA, Akira, WEI, Kaichun, WEI, Suwen, MORALEJO, Daniel H., OGINO, Tomoe, GAILLARD, Claude, SASAKI, Yoshiyuki, MATSUMOTO, Kozo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Glucose - analysis Chromosome Mapping Diabetes Mellitus - genetics Diabetes Mellitus, Type 2 - genetics epistasis Epistasis, Genetic genetic dissection Genetic Markers Genetic Predisposition to Disease Genotype Heterozygote Homozygote NIDDM Obesity OLETF rat Rats Rats, Inbred F344 Rats, Inbred OLETF
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