Identification and quantitation of sodium-thyroxine and its degradation products by LC using electrochemical and MS detection

High performance liquid chromatography (HPLC) was used in combination with an amperometric and mass spectrometric detection to elucidate and quantitate the degradation products and contaminants of the photo-sensitive Na-thyroxine. Using HPLC with amperometric detection, seven decomposition compounds...

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Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2001-07, Vol.25 (5-6), p.697-711
Hauptverfasser:	KAZEMIFARD, Amir G, MOORE, Douglas E, AGHAZADEH, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biological and medical sciences Chromatography, High Pressure Liquid - methods Electrochemistry General pharmacology Mass Spectrometry Medical sciences Pharmacology. Drug treatments Reference Standards Reproducibility of Results Sensitivity and Specificity Thyroxine - analysis
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