Directed vascular expression of the thromboxane A2 receptor results in intrauterine growth retardation

Thromboxane (Tx) A 2 is a platelet agonist, smooth muscle cell constrictor, and mitogen 1 . Urinary Tx metabolite (Tx-M) excretion is increased in syndromes of platelet activation and early in both normal pregnancies and in pregnancy-induced hypertension 2 , 3 . A further increment occurs in patient...

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