Patterns of retinal ganglion cell survival after brain-derived neurotrophic factor administration in hypertensive eyes of rats

We investigated the effect of brain-derived neurotrophic factor (BDNF) on retinal ganglion cell (RGC) survival after intraocular pressure (IOP) elevation at various time intervals. In adult Wistar rats, RGCs were labeled with 5% Fluorogold. Animals with 1.8–2.5-fold increase in IOP after cauterizati...

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Veröffentlicht in:	Neuroscience letters 2001-06, Vol.305 (2), p.139-142
Hauptverfasser:	Ko, Mei-Lan, Hu, Dan-Ning, Ritch, Robert, Sharma, S.C, Chen, Chau-Fong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Brain-derived neurotrophic factor Brain-Derived Neurotrophic Factor - administration & dosage Brain-Derived Neurotrophic Factor - pharmacology Cell Survival - drug effects Female Glaucoma Glaucoma - pathology Glaucoma - physiopathology Glaucoma and intraocular pressure Humans Hypertensive eye Injections Intraocular Pressure - drug effects Medical sciences Neuroprotective Agents - administration & dosage Neuroprotective Agents - pharmacology Ophthalmology Rats Rats, Wistar Recombinant Proteins - administration & dosage Recombinant Proteins - pharmacology Retinal ganglion cell Retinal Ganglion Cells - drug effects Retinal Ganglion Cells - physiology Vitreous Body
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