Identifying HOX paralog groups by the PBX-binding region

The Hox genes are a family of transcription factors that define specific anteroposterior identities, both in vertebrate and in invertebrate embryos, and that are characterized by a very highly conserved DNA-binding motif known as the homeodomain. In vitro, most HOX proteins recognize the same four-b...

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Veröffentlicht in:	Trends in genetics 2000-02, Vol.16 (2), p.66-67
Hauptverfasser:	Morgan, Richard, In der Rieden, Paul, Hooiveld, Michiel H.W, Durston, Antony J
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Binding Sites Conserved Sequence DNA-Binding Proteins - chemistry DNA-Binding Proteins - genetics DNA-binding specificity Evolution, Molecular extradenticle protein Homeodomain Proteins - chemistry Homeodomain Proteins - genetics Hox gene Hox paralog groups Hox protein Humans Molecular Sequence Data Multigene Family PBX protein PBX-binding region Transcription Factors - chemistry Transcription Factors - genetics
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