T Cells Overexpressing Interferon-γ and Interleukin-10 Are Found in Both the Thymus and Secondary Lymphoid Tissues of Feline Immunodeficiency Virus-Infected Cats

Similar to human immunodeficiency virus type 1, feline immunodeficiency virus (FIV) replicates in the thymus of infected animals, causing marked alteration in thymic lymphocyte subpopulations. The immune phenotype and cytokine patterns in the thymus and secondary lymphoid tissues of FIV-infected cat...

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Veröffentlicht in:	The Journal of infectious diseases 2000-02, Vol.181 (2), p.564-575
Hauptverfasser:	Liang, Yinghua, Hudson, Lola C., Levy, Julie K., Ritchey, Jerry W., Tompkins, Wayne A. F., Tompkins, Mary B.
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Animals B lymphocytes B-Lymphocytes - immunology Biological and medical sciences Cats CD4 antigen CD8 antigen Cytokines Experimental viral diseases and models Feline Acquired Immunodeficiency Syndrome - immunology Feline Acquired Immunodeficiency Syndrome - pathology feline immunodeficiency virus g-Interferon Gene Products, gag - metabolism Immunodeficiency Virus, Feline - immunology Immunohistochemistry In Situ Hybridization Infections Infectious diseases Interferon-gamma - biosynthesis Interferon-gamma - genetics Interleukin-10 - biosynthesis Interleukin-10 - genetics Lymph nodes Lymph Nodes - immunology Lymph Nodes - pathology Major Articles Medical sciences Messenger RNA Physiological immunosuppression Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics RNA, Messenger - metabolism T lymphocytes T-Lymphocyte Subsets - immunology Thymocytes Thymus Gland - immunology Thymus Gland - pathology Viral diseases Viruses
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