Concordance of deficit and non-deficit subtypes in siblings affected with schizophrenia
Deficit and non-deficit subtypes were examined for their concordance in 83 sibling pairs of 109 schizophrenic patients belonging to 46 multiply affected families. Using a sib-pair method, we have found that the distribution of deficit and non-deficit syndromes in sibling pairs of schizophrenic patie...
Gespeichert in:
Veröffentlicht in: | Psychiatry research 2001-05, Vol.102 (1), p.59-64 |
---|---|
Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 64 |
---|---|
container_issue | 1 |
container_start_page | 59 |
container_title | Psychiatry research |
container_volume | 102 |
creator | Fouldrin, Gaël Jay, Maurice Bonnet-Brilhault, Frédérique Ménard, Jean-François Petit, Michel Thibaut, Florence |
description | Deficit and non-deficit subtypes were examined for their concordance in 83 sibling pairs of 109 schizophrenic patients belonging to 46 multiply affected families. Using a sib-pair method, we have found that the distribution of deficit and non-deficit syndromes in sibling pairs of schizophrenic patients differed significantly from chance expectation. This familial aggregation suggests that the syndrome may be used to define phenotypes for genetic studies. |
doi_str_mv | 10.1016/S0165-1781(01)00248-7 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_70867489</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0165178101002487</els_id><sourcerecordid>70867489</sourcerecordid><originalsourceid>FETCH-LOGICAL-c389t-1742256db4b3e94cb714922f54f61f82e31d5ee623221bc42aa1d0c48ef7868d3</originalsourceid><addsrcrecordid>eNqFkN9rFDEQgEOxtGf1T6gEBLEPq5lsdpN9Ejm0Fgp9UPExZJOJF9lLzmRPaf96c961fSwMMwS--ZGPkHNg74BB__5rTV0DUsFbBheMcaEaeUQWoCRvJPD2GVk8IKfkeSm_WKVgGE7IKUDbKyXYgvxYpmhTdiZapMlThz7YMFMTHY0pNvfvsh3n2w0WGiItYZxC_Fmo8R7tjI7-DfOKFrsKd2mzyhiDeUGOvZkKvjzUM_L986dvyy_N9c3l1fLjdWNbNcz1OMF517tRjC0Owo4SxMC574TvwSuOLbgOsect5zBawY0Bx6xQ6KXqlWvPyJv93E1Ov7dYZr0OxeI0mYhpW7RkqpdCDRXs9qDNqZSMXm9yWJt8q4HpnVH936je6dKsxs6olrXv1WHBdlyje-w6KKzA6wNgijWTz1VlKA_coOqHdus_7CmsMv4EzLrYgFW6C7k61C6FJw75B9MpkkQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>70867489</pqid></control><display><type>article</type><title>Concordance of deficit and non-deficit subtypes in siblings affected with schizophrenia</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Fouldrin, Gaël ; Jay, Maurice ; Bonnet-Brilhault, Frédérique ; Ménard, Jean-François ; Petit, Michel ; Thibaut, Florence</creator><creatorcontrib>Fouldrin, Gaël ; Jay, Maurice ; Bonnet-Brilhault, Frédérique ; Ménard, Jean-François ; Petit, Michel ; Thibaut, Florence</creatorcontrib><description>Deficit and non-deficit subtypes were examined for their concordance in 83 sibling pairs of 109 schizophrenic patients belonging to 46 multiply affected families. Using a sib-pair method, we have found that the distribution of deficit and non-deficit syndromes in sibling pairs of schizophrenic patients differed significantly from chance expectation. This familial aggregation suggests that the syndrome may be used to define phenotypes for genetic studies.</description><identifier>ISSN: 0165-1781</identifier><identifier>EISSN: 1872-7123</identifier><identifier>DOI: 10.1016/S0165-1781(01)00248-7</identifier><identifier>PMID: 11368840</identifier><identifier>CODEN: PSRSDR</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>Adult ; Adult and adolescent clinical studies ; Biological and medical sciences ; Deficit/non-deficit categorization ; Family studies ; Female ; Humans ; Male ; Medical sciences ; Middle Aged ; Psychiatric Status Rating Scales ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Psychoses ; Schizophrenia ; Schizophrenia - diagnosis ; Schizophrenic Psychology ; Sib-pair ; Sibling Relations</subject><ispartof>Psychiatry research, 2001-05, Vol.102 (1), p.59-64</ispartof><rights>2001 Elsevier Science Ireland Ltd</rights><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c389t-1742256db4b3e94cb714922f54f61f82e31d5ee623221bc42aa1d0c48ef7868d3</citedby><cites>FETCH-LOGICAL-c389t-1742256db4b3e94cb714922f54f61f82e31d5ee623221bc42aa1d0c48ef7868d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0165-1781(01)00248-7$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=984929$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11368840$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fouldrin, Gaël</creatorcontrib><creatorcontrib>Jay, Maurice</creatorcontrib><creatorcontrib>Bonnet-Brilhault, Frédérique</creatorcontrib><creatorcontrib>Ménard, Jean-François</creatorcontrib><creatorcontrib>Petit, Michel</creatorcontrib><creatorcontrib>Thibaut, Florence</creatorcontrib><title>Concordance of deficit and non-deficit subtypes in siblings affected with schizophrenia</title><title>Psychiatry research</title><addtitle>Psychiatry Res</addtitle><description>Deficit and non-deficit subtypes were examined for their concordance in 83 sibling pairs of 109 schizophrenic patients belonging to 46 multiply affected families. Using a sib-pair method, we have found that the distribution of deficit and non-deficit syndromes in sibling pairs of schizophrenic patients differed significantly from chance expectation. This familial aggregation suggests that the syndrome may be used to define phenotypes for genetic studies.</description><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Biological and medical sciences</subject><subject>Deficit/non-deficit categorization</subject><subject>Family studies</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Psychiatric Status Rating Scales</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Psychoses</subject><subject>Schizophrenia</subject><subject>Schizophrenia - diagnosis</subject><subject>Schizophrenic Psychology</subject><subject>Sib-pair</subject><subject>Sibling Relations</subject><issn>0165-1781</issn><issn>1872-7123</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkN9rFDEQgEOxtGf1T6gEBLEPq5lsdpN9Ejm0Fgp9UPExZJOJF9lLzmRPaf96c961fSwMMwS--ZGPkHNg74BB__5rTV0DUsFbBheMcaEaeUQWoCRvJPD2GVk8IKfkeSm_WKVgGE7IKUDbKyXYgvxYpmhTdiZapMlThz7YMFMTHY0pNvfvsh3n2w0WGiItYZxC_Fmo8R7tjI7-DfOKFrsKd2mzyhiDeUGOvZkKvjzUM_L986dvyy_N9c3l1fLjdWNbNcz1OMF517tRjC0Owo4SxMC574TvwSuOLbgOsect5zBawY0Bx6xQ6KXqlWvPyJv93E1Ov7dYZr0OxeI0mYhpW7RkqpdCDRXs9qDNqZSMXm9yWJt8q4HpnVH936je6dKsxs6olrXv1WHBdlyje-w6KKzA6wNgijWTz1VlKA_coOqHdus_7CmsMv4EzLrYgFW6C7k61C6FJw75B9MpkkQ</recordid><startdate>20010510</startdate><enddate>20010510</enddate><creator>Fouldrin, Gaël</creator><creator>Jay, Maurice</creator><creator>Bonnet-Brilhault, Frédérique</creator><creator>Ménard, Jean-François</creator><creator>Petit, Michel</creator><creator>Thibaut, Florence</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20010510</creationdate><title>Concordance of deficit and non-deficit subtypes in siblings affected with schizophrenia</title><author>Fouldrin, Gaël ; Jay, Maurice ; Bonnet-Brilhault, Frédérique ; Ménard, Jean-François ; Petit, Michel ; Thibaut, Florence</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c389t-1742256db4b3e94cb714922f54f61f82e31d5ee623221bc42aa1d0c48ef7868d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Biological and medical sciences</topic><topic>Deficit/non-deficit categorization</topic><topic>Family studies</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Psychiatric Status Rating Scales</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Psychoses</topic><topic>Schizophrenia</topic><topic>Schizophrenia - diagnosis</topic><topic>Schizophrenic Psychology</topic><topic>Sib-pair</topic><topic>Sibling Relations</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fouldrin, Gaël</creatorcontrib><creatorcontrib>Jay, Maurice</creatorcontrib><creatorcontrib>Bonnet-Brilhault, Frédérique</creatorcontrib><creatorcontrib>Ménard, Jean-François</creatorcontrib><creatorcontrib>Petit, Michel</creatorcontrib><creatorcontrib>Thibaut, Florence</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Psychiatry research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fouldrin, Gaël</au><au>Jay, Maurice</au><au>Bonnet-Brilhault, Frédérique</au><au>Ménard, Jean-François</au><au>Petit, Michel</au><au>Thibaut, Florence</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Concordance of deficit and non-deficit subtypes in siblings affected with schizophrenia</atitle><jtitle>Psychiatry research</jtitle><addtitle>Psychiatry Res</addtitle><date>2001-05-10</date><risdate>2001</risdate><volume>102</volume><issue>1</issue><spage>59</spage><epage>64</epage><pages>59-64</pages><issn>0165-1781</issn><eissn>1872-7123</eissn><coden>PSRSDR</coden><abstract>Deficit and non-deficit subtypes were examined for their concordance in 83 sibling pairs of 109 schizophrenic patients belonging to 46 multiply affected families. Using a sib-pair method, we have found that the distribution of deficit and non-deficit syndromes in sibling pairs of schizophrenic patients differed significantly from chance expectation. This familial aggregation suggests that the syndrome may be used to define phenotypes for genetic studies.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>11368840</pmid><doi>10.1016/S0165-1781(01)00248-7</doi><tpages>6</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0165-1781 |
ispartof | Psychiatry research, 2001-05, Vol.102 (1), p.59-64 |
issn | 0165-1781 1872-7123 |
language | eng |
recordid | cdi_proquest_miscellaneous_70867489 |
source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
subjects | Adult Adult and adolescent clinical studies Biological and medical sciences Deficit/non-deficit categorization Family studies Female Humans Male Medical sciences Middle Aged Psychiatric Status Rating Scales Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Schizophrenia Schizophrenia - diagnosis Schizophrenic Psychology Sib-pair Sibling Relations |
title | Concordance of deficit and non-deficit subtypes in siblings affected with schizophrenia |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T07%3A31%3A30IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Concordance%20of%20deficit%20and%20non-deficit%20subtypes%20in%20siblings%20affected%20with%20schizophrenia&rft.jtitle=Psychiatry%20research&rft.au=Fouldrin,%20Ga%C3%ABl&rft.date=2001-05-10&rft.volume=102&rft.issue=1&rft.spage=59&rft.epage=64&rft.pages=59-64&rft.issn=0165-1781&rft.eissn=1872-7123&rft.coden=PSRSDR&rft_id=info:doi/10.1016/S0165-1781(01)00248-7&rft_dat=%3Cproquest_cross%3E70867489%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=70867489&rft_id=info:pmid/11368840&rft_els_id=S0165178101002487&rfr_iscdi=true |