14-3-3 Is Involved in p75 Neurotrophin Receptor-mediated Signal Transduction

The low affinity neurotrophin receptor (p75NTR) has been shown to mediate the apoptosis signaling to neural cells. However, the specific mechanisms of intracellular signal transduction of this process are largely unknown. To understand p75NTR-mediated signal transduction, we previously identified a...

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Veröffentlicht in:	The Journal of biological chemistry 2001-05, Vol.276 (20), p.17291-17300
Hauptverfasser:	Kimura, Makoto T., Irie, Shinji, Shoji-Hoshino, Shisako, Mukai, Jun, Nadano, Daita, Oshimura, Mitsuo, Sato, Taka-Aki
Format:	Artikel
Sprache:	eng
Schlagworte:	14-3-3 Proteins Animals Apoptosis - drug effects Apoptosis - physiology Apoptosis Regulatory Proteins Binding Sites Cell Line Embryo, Mammalian Gene Library Humans Kinetics Mice Nerve Growth Factor - pharmacology Oligodendroglia - physiology PC12 Cells Proteins - metabolism Rats Receptor, Nerve Growth Factor Receptors, Nerve Growth Factor - physiology Recombinant Proteins - metabolism Signal Transduction - drug effects Signal Transduction - physiology Transfection Tyrosine 3-Monooxygenase - metabolism
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