Polymer-assisted solution-phase (PASP) library synthesis of α-ketoamides

A parallel solution‐phase library synthesis of α‐ketoamides is described. The two‐step library synthesis is accomplished using polymer‐assisted solution‐phase (PASP) synthesis techniques. This high‐yielding, multi‐step sequence utilizes sequestering resins for the removal of reactants, reactant by‐p...

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Veröffentlicht in:	Biotechnology and bioengineering 2000, Vol.71 (1), p.51-57
Hauptverfasser:	South, Michael S., Dice, Thomas A., Parlow, John J.
Format:	Artikel
Sprache:	eng
Schlagworte:	a-hydroxy acid a-ketoamides amide coupling Amides - chemical synthesis Amides - chemistry Byproducts Databases as Topic Evaporation Filtration Ketones Ketones - chemical synthesis Models, Molecular Molecular Conformation multi-step library synthesis periodinane periodinane oxidation polymer-assisted solution-phase (PASP) chemical library synthesis Polymers Resins Solutions α-ketoamides
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