Conserved protein motifs and structural organization of a fish gene homologous to mammalian apolipoprotein E

Apolipoprotein E (apoE) plays a central role in lipid metabolism from its ability to interact with lipoprotein receptors. Besides its role in cardiovascular diseases, apoE polymorphism contributes to susceptibility to neurodegenerative diseases, such as Alzheimer's disease. The statistical sign...

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Veröffentlicht in:	European journal of biochemistry 2000-01, Vol.267 (2), p.549-559
Hauptverfasser:	Durliat, Michèle, André, Michèle, Babin, Patrick J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Motifs Amino Acid Sequence Animals APOE gene apolipoprotein Apolipoproteins E - genetics Apolipoproteins E - metabolism Base Sequence Conserved Sequence Danio rerio Exons Fishes - genetics Freshwater Gene Expression Regulation Humans Introns lipoprotein Mammals - genetics Molecular Sequence Data Oncorhynchus mykiss - genetics protein motifs Restriction Mapping Sequence Homology, Amino Acid trout zebrafish Zebrafish - genetics
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