A Cyclophilin B Gene Encodes Antigenic Epitopes Recognized by HLA-A24-Restricted and Tumor-Specific CTLs

We have studied Ags recognized by HLA class I-restricted CTLs established from tumor site to better understand the molecular basis of tumor immunology. HLA-A24-restricted and tumor-specific CTLs established from T cells infiltrating into lung adenocarcinoma recognized the two antigenic peptides enco...

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Veröffentlicht in:	The Journal of immunology (1950) 1999-11, Vol.163 (9), p.4994-5004
Hauptverfasser:	Gomi, Shinya, Nakao, Masanobu, Niiya, Fumihiko, Imamura, Yutaka, Kawano, Kouichiro, Nishizaka, Shinya, Hayashi, Akihiko, Sobao, Yuji, Oizumi, Kotaro, Itoh, Kyogo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Antigens, Neoplasm - immunology Cyclophilins Cytotoxicity, Immunologic - immunology Epitopes, T-Lymphocyte - genetics Epitopes, T-Lymphocyte - metabolism HLA-A Antigens - biosynthesis HLA-A Antigens - immunology HLA-A24 Antigen Humans Immunophilins - genetics Immunophilins - immunology Interferon-gamma - biosynthesis Lung Neoplasms Lymphocyte Count Oligopeptides - immunology Oligopeptides - metabolism Oligopeptides - pharmacology Peptidylprolyl Isomerase Protein Binding - immunology Receptors, Antigen, T-Cell, alpha-beta - immunology Stem Cells - cytology T-Lymphocytes, Cytotoxic - immunology T-Lymphocytes, Cytotoxic - metabolism Tumor Cells, Cultured
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