Prediction of highly skin smear positive' cases among MB leprosy patients using clinical parameters
Although 'highly skin smear positive' MB leprosy cases are known to be at high risk of relapse after release from treatment, and have been recommended to receive 'prolonged duration' MDT, government field-based control programmes without skin smear facilities have no simple alter...
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| Veröffentlicht in: | Leprosy review 2001-03, Vol.72 (1), p.23-28 |
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| container_title | Leprosy review |
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| creator | LEMASTER, Joseph W SHWE, Tin BUTLIN, C. Ruth ROCHE, Paul W |
| description | Although 'highly skin smear positive' MB leprosy cases are known to be at high risk of relapse after release from treatment, and have been recommended to receive 'prolonged duration' MDT, government field-based control programmes without skin smear facilities have no simple alternative method to detect such cases. This study reports a significant prevalence of 'highly smear positive' cases amongst 2374 new multibacillary cases recently surveyed by skin smears in Nepal, and retrospectively analyses 555 newly detected, previously untreated BL and LL cases to identify clinical and laboratory parameters that may be associated with a 'highly positive skin smear'. While some parameters showed high sensitivity in predicting 'highly positive smear' status, none showed both high sensitivity and high specificity simultaneously. |
| doi_str_mv | 10.5935/0305-7518.20010005 |
| format | Article |
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Ruth</au><au>ROCHE, Paul W</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prediction of highly skin smear positive' cases among MB leprosy patients using clinical parameters</atitle><jtitle>Leprosy review</jtitle><addtitle>Lepr Rev</addtitle><date>2001-03-01</date><risdate>2001</risdate><volume>72</volume><issue>1</issue><spage>23</spage><epage>28</epage><pages>23-28</pages><issn>0305-7518</issn><eissn>2162-8807</eissn><coden>LEREAA</coden><abstract>Although 'highly skin smear positive' MB leprosy cases are known to be at high risk of relapse after release from treatment, and have been recommended to receive 'prolonged duration' MDT, government field-based control programmes without skin smear facilities have no simple alternative method to detect such cases. 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| ispartof | Leprosy review, 2001-03, Vol.72 (1), p.23-28 |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adult Bacterial diseases Biological and medical sciences Female Human bacterial diseases Humans Infectious diseases Leprosy Leprosy - diagnosis Male Medical sciences Physical Examination - standards Predictive Value of Tests Sensitivity and Specificity Tropical bacterial diseases Tropical medicine |
| title | Prediction of highly skin smear positive' cases among MB leprosy patients using clinical parameters |
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