Type A behavior and coronary atherosclerosis
Objectives: To evaluate whether the pathogenesis of type A behavior may involve the premature development of coronary atherosclerosis. Background: Type A or coronary-prone behavior is considered a possible risk factor for the development of coronary heart disease. Premature development of coronary a...
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| Veröffentlicht in: | Atherosclerosis 2001-05, Vol.156 (1), p.145-149 |
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| container_issue | 1 |
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| container_title | Atherosclerosis |
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| creator | Sparagon, Barton Friedman, Meyer Breall, William S. Lou Goodwin, M. Fleischmann, Nancy Ghandour, Ghassan |
| description | Objectives: To evaluate whether the pathogenesis of type A behavior may involve the premature development of coronary atherosclerosis.
Background: Type A or coronary-prone behavior is considered a possible risk factor for the development of coronary heart disease. Premature development of coronary atherosclerosis is suspected to play a role. Utilizing electron beam computed tomography, one can accurately determine the degree of coronary artery calcification, which is reflective of coronary atherosclerosis.
Methods: We performed a study of 35 men who had no clinical evidence of coronary heart disease. Twenty exhibited severe type A behavior and 15 exhibited type B behavior. All subjects were given an Electron Beam Computed Tomography scan of their coronary arteries and a treadmill electrocardiogram.
Results: Eight of the 20 (40%) type A subjects were found to have coronary calcification compared to none of the type B subjects (
P=0.005). The correlation coefficient between type A score and coronary calcium score was 0.39 (
P=0.09).
Conclusions: The pathophysiology by which type A behavior increases the risk for coronary heart disease may involve the premature development of coronary atherosclerosis. |
| doi_str_mv | 10.1016/S0021-9150(00)00604-3 |
| format | Article |
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Background: Type A or coronary-prone behavior is considered a possible risk factor for the development of coronary heart disease. Premature development of coronary atherosclerosis is suspected to play a role. Utilizing electron beam computed tomography, one can accurately determine the degree of coronary artery calcification, which is reflective of coronary atherosclerosis.
Methods: We performed a study of 35 men who had no clinical evidence of coronary heart disease. Twenty exhibited severe type A behavior and 15 exhibited type B behavior. All subjects were given an Electron Beam Computed Tomography scan of their coronary arteries and a treadmill electrocardiogram.
Results: Eight of the 20 (40%) type A subjects were found to have coronary calcification compared to none of the type B subjects (
P=0.005). The correlation coefficient between type A score and coronary calcium score was 0.39 (
P=0.09).
Conclusions: The pathophysiology by which type A behavior increases the risk for coronary heart disease may involve the premature development of coronary atherosclerosis.</description><identifier>ISSN: 0021-9150</identifier><identifier>EISSN: 1879-1484</identifier><identifier>DOI: 10.1016/S0021-9150(00)00604-3</identifier><identifier>PMID: 11369007</identifier><language>eng</language><publisher>Amsterdam: Elsevier Ireland Ltd</publisher><subject>Biological and medical sciences ; Calcinosis - diagnosis ; Calcinosis - psychology ; Cardiology. Vascular system ; Coronary Angiography ; Coronary Artery Disease - diagnosis ; Coronary Artery Disease - psychology ; Coronary atherosclerosis ; Coronary Disease - diagnosis ; Coronary Disease - psychology ; Coronary heart disease ; Electrocardiography ; Exercise Test ; Heart ; Humans ; Male ; Medical sciences ; Middle Aged ; Risk Factors ; Tomography, X-Ray Computed ; Type A behavior ; Type A Personality</subject><ispartof>Atherosclerosis, 2001-05, Vol.156 (1), p.145-149</ispartof><rights>2001 Elsevier Science Ireland Ltd</rights><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c389t-d1b9272ac8ca08a6ac6a479cf8bdc1237e14696fd86ebb01de42814f145852363</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0021-9150(00)00604-3$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>309,310,314,780,784,789,790,3550,23930,23931,25140,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=978443$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11369007$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sparagon, Barton</creatorcontrib><creatorcontrib>Friedman, Meyer</creatorcontrib><creatorcontrib>Breall, William S.</creatorcontrib><creatorcontrib>Lou Goodwin, M.</creatorcontrib><creatorcontrib>Fleischmann, Nancy</creatorcontrib><creatorcontrib>Ghandour, Ghassan</creatorcontrib><title>Type A behavior and coronary atherosclerosis</title><title>Atherosclerosis</title><addtitle>Atherosclerosis</addtitle><description>Objectives: To evaluate whether the pathogenesis of type A behavior may involve the premature development of coronary atherosclerosis.
Background: Type A or coronary-prone behavior is considered a possible risk factor for the development of coronary heart disease. Premature development of coronary atherosclerosis is suspected to play a role. Utilizing electron beam computed tomography, one can accurately determine the degree of coronary artery calcification, which is reflective of coronary atherosclerosis.
Methods: We performed a study of 35 men who had no clinical evidence of coronary heart disease. Twenty exhibited severe type A behavior and 15 exhibited type B behavior. All subjects were given an Electron Beam Computed Tomography scan of their coronary arteries and a treadmill electrocardiogram.
Results: Eight of the 20 (40%) type A subjects were found to have coronary calcification compared to none of the type B subjects (
P=0.005). The correlation coefficient between type A score and coronary calcium score was 0.39 (
P=0.09).
Conclusions: The pathophysiology by which type A behavior increases the risk for coronary heart disease may involve the premature development of coronary atherosclerosis.</description><subject>Biological and medical sciences</subject><subject>Calcinosis - diagnosis</subject><subject>Calcinosis - psychology</subject><subject>Cardiology. Vascular system</subject><subject>Coronary Angiography</subject><subject>Coronary Artery Disease - diagnosis</subject><subject>Coronary Artery Disease - psychology</subject><subject>Coronary atherosclerosis</subject><subject>Coronary Disease - diagnosis</subject><subject>Coronary Disease - psychology</subject><subject>Coronary heart disease</subject><subject>Electrocardiography</subject><subject>Exercise Test</subject><subject>Heart</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Risk Factors</subject><subject>Tomography, X-Ray Computed</subject><subject>Type A behavior</subject><subject>Type A Personality</subject><issn>0021-9150</issn><issn>1879-1484</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1Lw0AQhhdRtFZ_ghIQRMHoTLLZ3ZykFL-g4MF6XjabCV1Jk7rbFvrvTWypR2GYuTwz8_IwdoFwj4Di4QMgwTjHDG4AbgEE8Dg9YANUMo-RK37IBnvkhJ2G8AUAXKI6ZieIqcgB5IDdTTcLikZRQTOzdq2PTFNGtvVtY_wmMssZ-TbYuu8unLGjytSBzndzyD6fn6bj13jy_vI2Hk1im6p8GZdY5IlMjFXWgDLCWGG4zG2litJikkpCLnJRlUpQUQCWxBOFvEKeqSxJRTpk19u7C99-rygs9dwFS3VtGmpXQUtQmUpRdmC2BW2XL3iq9MK7eZdcI-hek_7VpHsHGvrqNOm027vcPVgVcyr_tnZeOuBqB5hgTV1501gX9lwuFef9mcctRZ2MtSOvg3XUWCqdJ7vUZev-CfIDDomCEg</recordid><startdate>20010501</startdate><enddate>20010501</enddate><creator>Sparagon, Barton</creator><creator>Friedman, Meyer</creator><creator>Breall, William S.</creator><creator>Lou Goodwin, M.</creator><creator>Fleischmann, Nancy</creator><creator>Ghandour, Ghassan</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20010501</creationdate><title>Type A behavior and coronary atherosclerosis</title><author>Sparagon, Barton ; Friedman, Meyer ; Breall, William S. ; Lou Goodwin, M. ; Fleischmann, Nancy ; Ghandour, Ghassan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c389t-d1b9272ac8ca08a6ac6a479cf8bdc1237e14696fd86ebb01de42814f145852363</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Biological and medical sciences</topic><topic>Calcinosis - diagnosis</topic><topic>Calcinosis - psychology</topic><topic>Cardiology. Vascular system</topic><topic>Coronary Angiography</topic><topic>Coronary Artery Disease - diagnosis</topic><topic>Coronary Artery Disease - psychology</topic><topic>Coronary atherosclerosis</topic><topic>Coronary Disease - diagnosis</topic><topic>Coronary Disease - psychology</topic><topic>Coronary heart disease</topic><topic>Electrocardiography</topic><topic>Exercise Test</topic><topic>Heart</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Risk Factors</topic><topic>Tomography, X-Ray Computed</topic><topic>Type A behavior</topic><topic>Type A Personality</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sparagon, Barton</creatorcontrib><creatorcontrib>Friedman, Meyer</creatorcontrib><creatorcontrib>Breall, William S.</creatorcontrib><creatorcontrib>Lou Goodwin, M.</creatorcontrib><creatorcontrib>Fleischmann, Nancy</creatorcontrib><creatorcontrib>Ghandour, Ghassan</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Atherosclerosis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sparagon, Barton</au><au>Friedman, Meyer</au><au>Breall, William S.</au><au>Lou Goodwin, M.</au><au>Fleischmann, Nancy</au><au>Ghandour, Ghassan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Type A behavior and coronary atherosclerosis</atitle><jtitle>Atherosclerosis</jtitle><addtitle>Atherosclerosis</addtitle><date>2001-05-01</date><risdate>2001</risdate><volume>156</volume><issue>1</issue><spage>145</spage><epage>149</epage><pages>145-149</pages><issn>0021-9150</issn><eissn>1879-1484</eissn><abstract>Objectives: To evaluate whether the pathogenesis of type A behavior may involve the premature development of coronary atherosclerosis.
Background: Type A or coronary-prone behavior is considered a possible risk factor for the development of coronary heart disease. Premature development of coronary atherosclerosis is suspected to play a role. Utilizing electron beam computed tomography, one can accurately determine the degree of coronary artery calcification, which is reflective of coronary atherosclerosis.
Methods: We performed a study of 35 men who had no clinical evidence of coronary heart disease. Twenty exhibited severe type A behavior and 15 exhibited type B behavior. All subjects were given an Electron Beam Computed Tomography scan of their coronary arteries and a treadmill electrocardiogram.
Results: Eight of the 20 (40%) type A subjects were found to have coronary calcification compared to none of the type B subjects (
P=0.005). The correlation coefficient between type A score and coronary calcium score was 0.39 (
P=0.09).
Conclusions: The pathophysiology by which type A behavior increases the risk for coronary heart disease may involve the premature development of coronary atherosclerosis.</abstract><cop>Amsterdam</cop><pub>Elsevier Ireland Ltd</pub><pmid>11369007</pmid><doi>10.1016/S0021-9150(00)00604-3</doi><tpages>5</tpages></addata></record> |
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| ispartof | Atherosclerosis, 2001-05, Vol.156 (1), p.145-149 |
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| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Biological and medical sciences Calcinosis - diagnosis Calcinosis - psychology Cardiology. Vascular system Coronary Angiography Coronary Artery Disease - diagnosis Coronary Artery Disease - psychology Coronary atherosclerosis Coronary Disease - diagnosis Coronary Disease - psychology Coronary heart disease Electrocardiography Exercise Test Heart Humans Male Medical sciences Middle Aged Risk Factors Tomography, X-Ray Computed Type A behavior Type A Personality |
| title | Type A behavior and coronary atherosclerosis |
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