Caspase-3 Activity as a Prognostic Factor in Colorectal Carcinoma

Several techniques to determine apoptotic frequencies in tumors have been described. In this study, we report that biochemical detection of enzymatic caspase-3 activity is a simple and quantitative technique to measure apoptosis in colorectal tumor cells. The relevance of the level of apoptosis in c...

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Veröffentlicht in:	Laboratory investigation 2001-05, Vol.81 (5), p.681-688
Hauptverfasser:	Jonges, Liesbeth E, Nagelkerke, J Fred, Ensink, N Geeske, van der Velde, Edo A, Tollenaar, Rob A E M, Fleuren, Gert Jan, van de Velde, Cornelis J H, Morreau, Hans, Kuppen, Peter J K
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biological and medical sciences Biomarkers, Tumor - analysis Caspase 3 Caspases - analysis CD57 Antigens - analysis Colorectal Neoplasms - enzymology Colorectal Neoplasms - immunology Colorectal Neoplasms - pathology Digestive system Humans Immunohistochemistry Investigative techniques, diagnostic techniques (general aspects) Leukocyte Common Antigens - analysis Lymphocyte Count Lymphocyte Subsets - immunology Lymphocytes, Tumor-Infiltrating - immunology Medical sciences Neoplasm Recurrence, Local - enzymology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Prognosis Risk Factors
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