1H NMR Conformational Study of a Variety of α-Anomers of C5-Substituted 2′-Deoxyuridines: Comparison to Their Antiherpetic β Counterparts

Although α-nucleosides are not found in nucleic acid, they do occur as constituents of smaller molecules in living cells, e.g., in vitamin B12. There are now several examples of α-nucleosides exerting a biological activity in some instances equal to, or even exceeding, that of the corresponding β-an...

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Veröffentlicht in:	Biochemical and biophysical research communications 2001-05, Vol.283 (5), p.1142-1149
Hauptverfasser:	Poznański, Jarosław, Felczak, Krzysztof, Bretner, Maria, Kulikowski, Tadeusz, Remin, Mieczysław
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral Agents - chemistry Deoxyuridine - analogs & derivatives Deoxyuridine - chemistry Herpesviridae - drug effects Hydrogen Magnetic Resonance Spectroscopy Models, Molecular Molecular Conformation Stereoisomerism
Online-Zugang:	Volltext
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