Simple detection of severe coronary stenosis using transthoracic doppler echocardiography at rest
Coronary flow velocity can be measured by transthoracic Doppler echocardiography (TTDE). The purpose of this study was to detect severe coronary stenosis using the diastolic-to-systolic flow velocity ratio (DSVR) determined by TTDE at rest. We prospectively examined 190 consecutive patients with ang...
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| Veröffentlicht in: | The American journal of cardiology 2001-05, Vol.87 (9), p.1064-1068 |
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| creator | Higashiue, Shinichi Watanabe, Hiroyuki Yokoi, Yoshiaki Takeuchi, Kazuhide Yoshikawa, Junichi |
| description | Coronary flow velocity can be measured by transthoracic Doppler echocardiography (TTDE). The purpose of this study was to detect severe coronary stenosis using the diastolic-to-systolic flow velocity ratio (DSVR) determined by TTDE at rest. We prospectively examined 190 consecutive patients with angina pectoris for whom coronary angiography was planned. Doppler spectral tracings of flow velocity in the distal left anterior descending artery were recorded by TTDE at rest. The mean and peak DSVR values were computed using mean and peak coronary flow velocities. DSVR measurement by TTDE at rest was performed within 24 hours before angiography, and in patients who underwent coronary intervention it was performed again within 48 hours after the intervention. The success rate for DSVR measurement by TTDE was 83.7%. There were significant differences in peak DSVR and mean DSVR between the patients with severe stenosis (percent diameter stenosis >85%) and those without severe stenosis (1.3 ± 0.4 vs 1.9 ± 0.50 and 1.2 ± 0.4 vs 1.8 ± 0.5, respectively; p |
| doi_str_mv | 10.1016/S0002-9149(01)01462-X |
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The purpose of this study was to detect severe coronary stenosis using the diastolic-to-systolic flow velocity ratio (DSVR) determined by TTDE at rest. We prospectively examined 190 consecutive patients with angina pectoris for whom coronary angiography was planned. Doppler spectral tracings of flow velocity in the distal left anterior descending artery were recorded by TTDE at rest. The mean and peak DSVR values were computed using mean and peak coronary flow velocities. DSVR measurement by TTDE at rest was performed within 24 hours before angiography, and in patients who underwent coronary intervention it was performed again within 48 hours after the intervention. The success rate for DSVR measurement by TTDE was 83.7%. There were significant differences in peak DSVR and mean DSVR between the patients with severe stenosis (percent diameter stenosis >85%) and those without severe stenosis (1.3 ± 0.4 vs 1.9 ± 0.50 and 1.2 ± 0.4 vs 1.8 ± 0.5, respectively; p <0.0001). In the 17 patients with successful intervention, DSVR was significantly increased after the procedure (mean 1.2 ± 0.1 vs 2.0 ± 0.2; peak 1.2 ± 0.2 vs 2.0 ± 0.3, respectively; p <0.0001). For percent diameter stenosis >85%, the best cut-off points were 1.6 for peak DSVR (sensitivity 79.0%, specificity 75.7%) and 1.5 for mean DSVR (sensitivity 77.0%, specificity 77.9%). Thus, DSVR measurement by TTDE is a simple, noninvasive method for detection of severe coronary stenosis at rest.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/S0002-9149(01)01462-X</identifier><identifier>PMID: 11348603</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Aged ; Angina pectoris ; Angina Pectoris - diagnostic imaging ; Angina Pectoris - therapy ; Angioplasty ; Biological and medical sciences ; Blood Flow Velocity ; Cardiology. Vascular system ; Coronary Angiography ; Coronary Disease - diagnostic imaging ; Coronary heart disease ; Coronary vessels ; Echocardiography, Doppler ; Female ; Heart ; Humans ; Male ; Medical procedures ; Medical sciences ; Middle Aged ; Observer Variation ; Prospective Studies ; Rest ; Sensitivity and Specificity ; Ultrasonic imaging</subject><ispartof>The American journal of cardiology, 2001-05, Vol.87 (9), p.1064-1068</ispartof><rights>2001 Excerpta Medica Inc.</rights><rights>2001 INIST-CNRS</rights><rights>Copyright Elsevier Sequoia S.A. May 1, 2001</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c482t-bbab1ae3c7730dad0d4d25b1d5bea155ef6f586331296b3eb209a130156c34593</citedby><cites>FETCH-LOGICAL-c482t-bbab1ae3c7730dad0d4d25b1d5bea155ef6f586331296b3eb209a130156c34593</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S000291490101462X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,65309</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=969275$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11348603$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Higashiue, Shinichi</creatorcontrib><creatorcontrib>Watanabe, Hiroyuki</creatorcontrib><creatorcontrib>Yokoi, Yoshiaki</creatorcontrib><creatorcontrib>Takeuchi, Kazuhide</creatorcontrib><creatorcontrib>Yoshikawa, Junichi</creatorcontrib><title>Simple detection of severe coronary stenosis using transthoracic doppler echocardiography at rest</title><title>The American journal of cardiology</title><addtitle>Am J Cardiol</addtitle><description>Coronary flow velocity can be measured by transthoracic Doppler echocardiography (TTDE). The purpose of this study was to detect severe coronary stenosis using the diastolic-to-systolic flow velocity ratio (DSVR) determined by TTDE at rest. We prospectively examined 190 consecutive patients with angina pectoris for whom coronary angiography was planned. Doppler spectral tracings of flow velocity in the distal left anterior descending artery were recorded by TTDE at rest. The mean and peak DSVR values were computed using mean and peak coronary flow velocities. DSVR measurement by TTDE at rest was performed within 24 hours before angiography, and in patients who underwent coronary intervention it was performed again within 48 hours after the intervention. The success rate for DSVR measurement by TTDE was 83.7%. There were significant differences in peak DSVR and mean DSVR between the patients with severe stenosis (percent diameter stenosis >85%) and those without severe stenosis (1.3 ± 0.4 vs 1.9 ± 0.50 and 1.2 ± 0.4 vs 1.8 ± 0.5, respectively; p <0.0001). In the 17 patients with successful intervention, DSVR was significantly increased after the procedure (mean 1.2 ± 0.1 vs 2.0 ± 0.2; peak 1.2 ± 0.2 vs 2.0 ± 0.3, respectively; p <0.0001). For percent diameter stenosis >85%, the best cut-off points were 1.6 for peak DSVR (sensitivity 79.0%, specificity 75.7%) and 1.5 for mean DSVR (sensitivity 77.0%, specificity 77.9%). Thus, DSVR measurement by TTDE is a simple, noninvasive method for detection of severe coronary stenosis at rest.</description><subject>Adult</subject><subject>Aged</subject><subject>Angina pectoris</subject><subject>Angina Pectoris - diagnostic imaging</subject><subject>Angina Pectoris - therapy</subject><subject>Angioplasty</subject><subject>Biological and medical sciences</subject><subject>Blood Flow Velocity</subject><subject>Cardiology. Vascular system</subject><subject>Coronary Angiography</subject><subject>Coronary Disease - diagnostic imaging</subject><subject>Coronary heart disease</subject><subject>Coronary vessels</subject><subject>Echocardiography, Doppler</subject><subject>Female</subject><subject>Heart</subject><subject>Humans</subject><subject>Male</subject><subject>Medical procedures</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Observer Variation</subject><subject>Prospective Studies</subject><subject>Rest</subject><subject>Sensitivity and Specificity</subject><subject>Ultrasonic imaging</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1rFTEUhoMo9rb6E5SgILoYPWcyyUxWRUr9gIKLKnQXMsmZ3pS5kzGZKfTfm_ZeKrhxFQLPeXPyvIy9QviIgOrTJQDUlcZGvwf8ANiourp6wjbYtbpCjeIp2zwiR-w455tyRZTqOTtCFE2nQGyYvQy7eSTuaSG3hDjxOPBMt5SIu5jiZNMdzwtNMYfM1xyma74kO-VlG5N1wXEf5xKQOLltdDb5EK-Tnbd33C48UV5esGeDHTO9PJwn7NeX859n36qLH1-_n32-qFzT1UvV97ZHS8K1rQBvPfjG17JHL3uyKCUNapCdEgJrrXpBfQ3aooDyIScaqcUJe7fPnVP8vZaHzS5kR-NoJ4prNi10sgZQBXzzD3gT1zSV3UwtQLRto0WB5B5yKeacaDBzCrsiwyCY-wLMQwHm3q4BNA8FmKsy9_oQvvY78n-nDsYL8PYA2OzsOBSXLuRHTitdt7JQp3uKirHbQMlkF2hy5EMqPRkfw38W-QPsM6MN</recordid><startdate>20010501</startdate><enddate>20010501</enddate><creator>Higashiue, Shinichi</creator><creator>Watanabe, Hiroyuki</creator><creator>Yokoi, Yoshiaki</creator><creator>Takeuchi, Kazuhide</creator><creator>Yoshikawa, Junichi</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>M7Z</scope><scope>NAPCQ</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20010501</creationdate><title>Simple detection of severe coronary stenosis using transthoracic doppler echocardiography at rest</title><author>Higashiue, Shinichi ; Watanabe, Hiroyuki ; Yokoi, Yoshiaki ; Takeuchi, Kazuhide ; Yoshikawa, Junichi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c482t-bbab1ae3c7730dad0d4d25b1d5bea155ef6f586331296b3eb209a130156c34593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Angina pectoris</topic><topic>Angina Pectoris - diagnostic imaging</topic><topic>Angina Pectoris - therapy</topic><topic>Angioplasty</topic><topic>Biological and medical sciences</topic><topic>Blood Flow Velocity</topic><topic>Cardiology. Vascular system</topic><topic>Coronary Angiography</topic><topic>Coronary Disease - diagnostic imaging</topic><topic>Coronary heart disease</topic><topic>Coronary vessels</topic><topic>Echocardiography, Doppler</topic><topic>Female</topic><topic>Heart</topic><topic>Humans</topic><topic>Male</topic><topic>Medical procedures</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Observer Variation</topic><topic>Prospective Studies</topic><topic>Rest</topic><topic>Sensitivity and Specificity</topic><topic>Ultrasonic imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Higashiue, Shinichi</creatorcontrib><creatorcontrib>Watanabe, Hiroyuki</creatorcontrib><creatorcontrib>Yokoi, Yoshiaki</creatorcontrib><creatorcontrib>Takeuchi, Kazuhide</creatorcontrib><creatorcontrib>Yoshikawa, Junichi</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biochemistry Abstracts 1</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Higashiue, Shinichi</au><au>Watanabe, Hiroyuki</au><au>Yokoi, Yoshiaki</au><au>Takeuchi, Kazuhide</au><au>Yoshikawa, Junichi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Simple detection of severe coronary stenosis using transthoracic doppler echocardiography at rest</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>2001-05-01</date><risdate>2001</risdate><volume>87</volume><issue>9</issue><spage>1064</spage><epage>1068</epage><pages>1064-1068</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>Coronary flow velocity can be measured by transthoracic Doppler echocardiography (TTDE). The purpose of this study was to detect severe coronary stenosis using the diastolic-to-systolic flow velocity ratio (DSVR) determined by TTDE at rest. We prospectively examined 190 consecutive patients with angina pectoris for whom coronary angiography was planned. Doppler spectral tracings of flow velocity in the distal left anterior descending artery were recorded by TTDE at rest. The mean and peak DSVR values were computed using mean and peak coronary flow velocities. DSVR measurement by TTDE at rest was performed within 24 hours before angiography, and in patients who underwent coronary intervention it was performed again within 48 hours after the intervention. The success rate for DSVR measurement by TTDE was 83.7%. There were significant differences in peak DSVR and mean DSVR between the patients with severe stenosis (percent diameter stenosis >85%) and those without severe stenosis (1.3 ± 0.4 vs 1.9 ± 0.50 and 1.2 ± 0.4 vs 1.8 ± 0.5, respectively; p <0.0001). In the 17 patients with successful intervention, DSVR was significantly increased after the procedure (mean 1.2 ± 0.1 vs 2.0 ± 0.2; peak 1.2 ± 0.2 vs 2.0 ± 0.3, respectively; p <0.0001). For percent diameter stenosis >85%, the best cut-off points were 1.6 for peak DSVR (sensitivity 79.0%, specificity 75.7%) and 1.5 for mean DSVR (sensitivity 77.0%, specificity 77.9%). Thus, DSVR measurement by TTDE is a simple, noninvasive method for detection of severe coronary stenosis at rest.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>11348603</pmid><doi>10.1016/S0002-9149(01)01462-X</doi><tpages>5</tpages></addata></record> |
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| subjects | Adult Aged Angina pectoris Angina Pectoris - diagnostic imaging Angina Pectoris - therapy Angioplasty Biological and medical sciences Blood Flow Velocity Cardiology. Vascular system Coronary Angiography Coronary Disease - diagnostic imaging Coronary heart disease Coronary vessels Echocardiography, Doppler Female Heart Humans Male Medical procedures Medical sciences Middle Aged Observer Variation Prospective Studies Rest Sensitivity and Specificity Ultrasonic imaging |
| title | Simple detection of severe coronary stenosis using transthoracic doppler echocardiography at rest |
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