High glucose induces ventricular instability and increases vasomotor tone in rats

To investigate cardiac repolarization time in streptozotocin-induced diabetic rats and isolated hearts perfused with high glucose concentration. We studied the effects of streptozotocin-induced diabetes on the cardiac repolarisation time (Q-T interval) in Sprague-Dawley rats during a 4-day period of...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Diabetologia 2001-04, Vol.44 (4), p.464-470
Hauptverfasser:	D'AMICO, M, MARFELLA, R, NAPPO, F, DI FILIPPO, C, DE ANGELIS, L, BERRINO, L, ROSSI, F, GIUGLIANO, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arginine - pharmacology Associated diseases and complications Biological and medical sciences Blood Pressure Cardiovascular disease Catheters Coronary Circulation Diabetes Diabetes Mellitus, Experimental - blood Diabetes Mellitus, Experimental - physiopathology Diabetes. Impaired glucose tolerance Electrocardiography Endocrine pancreas. Apud cells (diseases) Endocrinopathies Endothelium Enzyme Inhibitors - pharmacology Glucose Glutathione - pharmacology Heart Heart - drug effects Heart - physiopathology Heart Rate Heart Ventricles - physiopathology Hyperglycemia Hyperglycemia - complications Hypotheses Insulin Male Medical sciences NG-Nitroarginine Methyl Ester - pharmacology Nitric oxide Nitric Oxide Synthase - antagonists & inhibitors Penicillin Rats Rats, Sprague-Dawley Vasomotor System - physiopathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!