Acquired tracheomalacia : Detection by expiratory CT scan

The purpose of this work was to determine whether cross-sectional area and coronal and sagittal diameter measurements of the trachea between inspiration and end-expiration on CT are significantly different between patients with acquired tracheomalacia and those without this condition. Inspiratory an...

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Veröffentlicht in:Journal of computer assisted tomography 2001-05, Vol.25 (3), p.394-399
Hauptverfasser: AQUINO, Suzanne L, SHEPARD, Jo-Anne O, GINNS, Leo C, MOORE, Richard H, HALPERN, Elkan, GRILLO, Hermes C, MCLOUD, Theresa C
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container_end_page 399
container_issue 3
container_start_page 394
container_title Journal of computer assisted tomography
container_volume 25
creator AQUINO, Suzanne L
SHEPARD, Jo-Anne O
GINNS, Leo C
MOORE, Richard H
HALPERN, Elkan
GRILLO, Hermes C
MCLOUD, Theresa C
description The purpose of this work was to determine whether cross-sectional area and coronal and sagittal diameter measurements of the trachea between inspiration and end-expiration on CT are significantly different between patients with acquired tracheomalacia and those without this condition. Inspiratory and end-expiratory CT scans of the trachea of 23 normal patients and 10 patients with acquired tracheomalacia were analyzed. Percent changes in cross-sectional area, coronal, and sagittal diameters were calculated. For patients with tracheomalacia, mean percent changes in the upper and middle trachea between inspiration and expiration were 49 and 44%; mean changes in the coronal and sagittal diameters in the upper and middle tracheal were 4 and 10% and 39 and 54%, respectively. Control group mean percent changes in the upper and middle tracheal area were 12 and 14%, respectively, and mean changes in the coronal and sagittal diameters in the upper and middle trachea were 4 and 4% and 11 and 13%, respectively. Significant differences were calculated for changes in cross-sectional area and sagittal diameter between groups (p < 10-5). Based on receiver operator curve analysis, a > 18% change in the upper trachea and 28% change in the midtrachea between inspiration and expiration were observed; the probability of tracheomalacia was 89-100%. The probability of tracheomalacia was > 89%, especially if the change in sagittal diameter was > 28%. By measuring changes in tracheal cross-sectional area and sagittal diameters between inspiratory and end-expiratory CT, a significant difference can be identified between normal patients and those with acquired tracheomalacia.
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Inspiratory and end-expiratory CT scans of the trachea of 23 normal patients and 10 patients with acquired tracheomalacia were analyzed. Percent changes in cross-sectional area, coronal, and sagittal diameters were calculated. For patients with tracheomalacia, mean percent changes in the upper and middle trachea between inspiration and expiration were 49 and 44%; mean changes in the coronal and sagittal diameters in the upper and middle tracheal were 4 and 10% and 39 and 54%, respectively. Control group mean percent changes in the upper and middle tracheal area were 12 and 14%, respectively, and mean changes in the coronal and sagittal diameters in the upper and middle trachea were 4 and 4% and 11 and 13%, respectively. Significant differences were calculated for changes in cross-sectional area and sagittal diameter between groups (p &lt; 10-5). Based on receiver operator curve analysis, a &gt; 18% change in the upper trachea and 28% change in the midtrachea between inspiration and expiration were observed; the probability of tracheomalacia was 89-100%. The probability of tracheomalacia was &gt; 89%, especially if the change in sagittal diameter was &gt; 28%. 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Nmr spectrometry</topic><topic>Respiratory Function Tests</topic><topic>Respiratory system</topic><topic>Respiratory system : syndromes and miscellaneous diseases</topic><topic>Retrospective Studies</topic><topic>ROC Curve</topic><topic>Sensitivity and Specificity</topic><topic>Tomography, X-Ray Computed</topic><topic>Trachea - diagnostic imaging</topic><topic>Tracheal Diseases - diagnostic imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>AQUINO, Suzanne L</creatorcontrib><creatorcontrib>SHEPARD, Jo-Anne O</creatorcontrib><creatorcontrib>GINNS, Leo C</creatorcontrib><creatorcontrib>MOORE, Richard H</creatorcontrib><creatorcontrib>HALPERN, Elkan</creatorcontrib><creatorcontrib>GRILLO, Hermes C</creatorcontrib><creatorcontrib>MCLOUD, Theresa C</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of computer assisted tomography</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>AQUINO, Suzanne L</au><au>SHEPARD, Jo-Anne O</au><au>GINNS, Leo C</au><au>MOORE, Richard H</au><au>HALPERN, Elkan</au><au>GRILLO, Hermes C</au><au>MCLOUD, Theresa C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Acquired tracheomalacia : Detection by expiratory CT scan</atitle><jtitle>Journal of computer assisted tomography</jtitle><addtitle>J Comput Assist Tomogr</addtitle><date>2001-05-01</date><risdate>2001</risdate><volume>25</volume><issue>3</issue><spage>394</spage><epage>399</epage><pages>394-399</pages><issn>0363-8715</issn><eissn>1532-3145</eissn><coden>JCATD5</coden><abstract>The purpose of this work was to determine whether cross-sectional area and coronal and sagittal diameter measurements of the trachea between inspiration and end-expiration on CT are significantly different between patients with acquired tracheomalacia and those without this condition. 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subjects Adult
Aged
Aged, 80 and over
Airway Obstruction - diagnostic imaging
Biological and medical sciences
Bronchoscopy
Case-Control Studies
Female
Humans
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Middle Aged
Pneumology
Prospective Studies
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Respiratory Function Tests
Respiratory system
Respiratory system : syndromes and miscellaneous diseases
Retrospective Studies
ROC Curve
Sensitivity and Specificity
Tomography, X-Ray Computed
Trachea - diagnostic imaging
Tracheal Diseases - diagnostic imaging
title Acquired tracheomalacia : Detection by expiratory CT scan
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