Improved neuromagnetic detection of fetal and neonatal auditory evoked responses
Objective: To assess the quality of fetal and neonatal auditory evoked responses (fAERs and nAERs) obtainable with a low-noise, high-channel count SQUID gradiometer in a well-shielded environment. Methods: Measurement of long-latency fAERs was attempted in 19 normal fetuses in 28 sessions at 29–40 w...
Gespeichert in:
| Veröffentlicht in: | Clinical neurophysiology 2001-05, Vol.112 (5), p.785-792 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 792 |
|---|---|
| container_issue | 5 |
| container_start_page | 785 |
| container_title | Clinical neurophysiology |
| container_volume | 112 |
| creator | Lengle, J.M Chen, M Wakai, R.T |
| description | Objective: To assess the quality of fetal and neonatal auditory evoked responses (fAERs and nAERs) obtainable with a low-noise, high-channel count SQUID gradiometer in a well-shielded environment.
Methods: Measurement of long-latency fAERs was attempted in 19 normal fetuses in 28 sessions at 29–40 weeks’ gestation, using a 37-channel SQUID gradiometer. Postnatal measurement was attempted in 16 neonates in 25 sessions at age 2–6 weeks.
Results: Signals of amplitude 8 fT or greater were detected in 15 of 28 fetal measurement sessions, yielding a higher success rate (54%) than in a previous study of ours. Signals of amplitude greater than 25 fT were detected in 23 of 25 (92%) of neonatal measurement sessions. The spatial and temporal characteristics of the signals were studied in greater detail. Dipole patterns consistent with a source in the auditory cortex were observable in nearly all neonates and in many fetuses. The dominant component of the nAER was compatible with the P250 seen in neonatal EEG recordings; however, the largest component of the fAERs had longer latency and in many subjects had opposite polarity.
Conclusion: A higher success rate, earlier detection, and improved characterization of signal morphology and topography were demonstrated for fAER recordings. |
| doi_str_mv | 10.1016/S1388-2457(01)00532-6 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_70841796</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1388245701005326</els_id><sourcerecordid>70841796</sourcerecordid><originalsourceid>FETCH-LOGICAL-c390t-d0cdf0b02ec7067bb0fa2a1acb38eed4f9bc36365c62554da205aec6faaf1f313</originalsourceid><addsrcrecordid>eNqFkM1q3TAQhUVoyV_7CAlelJIunI4kW7ZXoYS2CQQaaLsWY2kUlNrWrWRfyNtX9yeku6w0gu_MHD7GzjhccuDq808u27YUVd1cAP8EUEtRqgN2zNtGlG1Xizd5fkaO2ElKjwDQQCUO2RHnUqq2k8fs_nZcxbAmW0y0xDDiw0SzN4Wlmczsw1QEVziacShw2kBhwu1nsX4O8amgdfiT05HSKkyJ0jv21uGQ6P3-PWW_v339dX1T3v34fnv95a40soO5tGCsgx4EmQZU0_fgUCBH08uWyFau641UUtVGibquLAqokYxyiI47yeUp-7jbm-v_XSjNevTJ0DBg7rgk3UBb8aZTGax3oIkhpUhOr6IfMT5pDnqjUm9V6o0nDVxvVepN7nx_YOlHsi-pvbsMfNgDmAwOLuJkfPqPE5VSkLGrHUbZxtpT1Ml4mgxZH7NibYN_pck_aqySDA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>70841796</pqid></control><display><type>article</type><title>Improved neuromagnetic detection of fetal and neonatal auditory evoked responses</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Lengle, J.M ; Chen, M ; Wakai, R.T</creator><creatorcontrib>Lengle, J.M ; Chen, M ; Wakai, R.T</creatorcontrib><description>Objective: To assess the quality of fetal and neonatal auditory evoked responses (fAERs and nAERs) obtainable with a low-noise, high-channel count SQUID gradiometer in a well-shielded environment.
Methods: Measurement of long-latency fAERs was attempted in 19 normal fetuses in 28 sessions at 29–40 weeks’ gestation, using a 37-channel SQUID gradiometer. Postnatal measurement was attempted in 16 neonates in 25 sessions at age 2–6 weeks.
Results: Signals of amplitude 8 fT or greater were detected in 15 of 28 fetal measurement sessions, yielding a higher success rate (54%) than in a previous study of ours. Signals of amplitude greater than 25 fT were detected in 23 of 25 (92%) of neonatal measurement sessions. The spatial and temporal characteristics of the signals were studied in greater detail. Dipole patterns consistent with a source in the auditory cortex were observable in nearly all neonates and in many fetuses. The dominant component of the nAER was compatible with the P250 seen in neonatal EEG recordings; however, the largest component of the fAERs had longer latency and in many subjects had opposite polarity.
Conclusion: A higher success rate, earlier detection, and improved characterization of signal morphology and topography were demonstrated for fAER recordings.</description><identifier>ISSN: 1388-2457</identifier><identifier>EISSN: 1872-8952</identifier><identifier>DOI: 10.1016/S1388-2457(01)00532-6</identifier><identifier>PMID: 11336893</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>Acoustic Stimulation ; Biological and medical sciences ; Brain - embryology ; Brain - physiology ; Electrodiagnosis. Electric activity recording ; Electroencephalography ; Evoked Potentials, Auditory - physiology ; Female ; Fetal auditory evoked responses ; Fetal brain activity ; Fetal magnetoencephalography ; Fetus - physiology ; Gestational Age ; Humans ; Infant ; Infant, Newborn - physiology ; Investigative techniques, diagnostic techniques (general aspects) ; Magnetoencephalography ; Medical sciences ; Neonatal brain activity ; Nervous system ; Pregnancy ; Reaction Time ; Single-trial evoked responses</subject><ispartof>Clinical neurophysiology, 2001-05, Vol.112 (5), p.785-792</ispartof><rights>2001 Elsevier Science Ireland Ltd</rights><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c390t-d0cdf0b02ec7067bb0fa2a1acb38eed4f9bc36365c62554da205aec6faaf1f313</citedby><cites>FETCH-LOGICAL-c390t-d0cdf0b02ec7067bb0fa2a1acb38eed4f9bc36365c62554da205aec6faaf1f313</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S1388-2457(01)00532-6$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>310,311,315,781,785,790,791,3551,23935,23936,25145,27929,27930,46000</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1124660$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11336893$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lengle, J.M</creatorcontrib><creatorcontrib>Chen, M</creatorcontrib><creatorcontrib>Wakai, R.T</creatorcontrib><title>Improved neuromagnetic detection of fetal and neonatal auditory evoked responses</title><title>Clinical neurophysiology</title><addtitle>Clin Neurophysiol</addtitle><description>Objective: To assess the quality of fetal and neonatal auditory evoked responses (fAERs and nAERs) obtainable with a low-noise, high-channel count SQUID gradiometer in a well-shielded environment.
Methods: Measurement of long-latency fAERs was attempted in 19 normal fetuses in 28 sessions at 29–40 weeks’ gestation, using a 37-channel SQUID gradiometer. Postnatal measurement was attempted in 16 neonates in 25 sessions at age 2–6 weeks.
Results: Signals of amplitude 8 fT or greater were detected in 15 of 28 fetal measurement sessions, yielding a higher success rate (54%) than in a previous study of ours. Signals of amplitude greater than 25 fT were detected in 23 of 25 (92%) of neonatal measurement sessions. The spatial and temporal characteristics of the signals were studied in greater detail. Dipole patterns consistent with a source in the auditory cortex were observable in nearly all neonates and in many fetuses. The dominant component of the nAER was compatible with the P250 seen in neonatal EEG recordings; however, the largest component of the fAERs had longer latency and in many subjects had opposite polarity.
Conclusion: A higher success rate, earlier detection, and improved characterization of signal morphology and topography were demonstrated for fAER recordings.</description><subject>Acoustic Stimulation</subject><subject>Biological and medical sciences</subject><subject>Brain - embryology</subject><subject>Brain - physiology</subject><subject>Electrodiagnosis. Electric activity recording</subject><subject>Electroencephalography</subject><subject>Evoked Potentials, Auditory - physiology</subject><subject>Female</subject><subject>Fetal auditory evoked responses</subject><subject>Fetal brain activity</subject><subject>Fetal magnetoencephalography</subject><subject>Fetus - physiology</subject><subject>Gestational Age</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn - physiology</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Magnetoencephalography</subject><subject>Medical sciences</subject><subject>Neonatal brain activity</subject><subject>Nervous system</subject><subject>Pregnancy</subject><subject>Reaction Time</subject><subject>Single-trial evoked responses</subject><issn>1388-2457</issn><issn>1872-8952</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM1q3TAQhUVoyV_7CAlelJIunI4kW7ZXoYS2CQQaaLsWY2kUlNrWrWRfyNtX9yeku6w0gu_MHD7GzjhccuDq808u27YUVd1cAP8EUEtRqgN2zNtGlG1Xizd5fkaO2ElKjwDQQCUO2RHnUqq2k8fs_nZcxbAmW0y0xDDiw0SzN4Wlmczsw1QEVziacShw2kBhwu1nsX4O8amgdfiT05HSKkyJ0jv21uGQ6P3-PWW_v339dX1T3v34fnv95a40soO5tGCsgx4EmQZU0_fgUCBH08uWyFau641UUtVGibquLAqokYxyiI47yeUp-7jbm-v_XSjNevTJ0DBg7rgk3UBb8aZTGax3oIkhpUhOr6IfMT5pDnqjUm9V6o0nDVxvVepN7nx_YOlHsi-pvbsMfNgDmAwOLuJkfPqPE5VSkLGrHUbZxtpT1Ml4mgxZH7NibYN_pck_aqySDA</recordid><startdate>20010501</startdate><enddate>20010501</enddate><creator>Lengle, J.M</creator><creator>Chen, M</creator><creator>Wakai, R.T</creator><general>Elsevier Ireland Ltd</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20010501</creationdate><title>Improved neuromagnetic detection of fetal and neonatal auditory evoked responses</title><author>Lengle, J.M ; Chen, M ; Wakai, R.T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c390t-d0cdf0b02ec7067bb0fa2a1acb38eed4f9bc36365c62554da205aec6faaf1f313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Acoustic Stimulation</topic><topic>Biological and medical sciences</topic><topic>Brain - embryology</topic><topic>Brain - physiology</topic><topic>Electrodiagnosis. Electric activity recording</topic><topic>Electroencephalography</topic><topic>Evoked Potentials, Auditory - physiology</topic><topic>Female</topic><topic>Fetal auditory evoked responses</topic><topic>Fetal brain activity</topic><topic>Fetal magnetoencephalography</topic><topic>Fetus - physiology</topic><topic>Gestational Age</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn - physiology</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Magnetoencephalography</topic><topic>Medical sciences</topic><topic>Neonatal brain activity</topic><topic>Nervous system</topic><topic>Pregnancy</topic><topic>Reaction Time</topic><topic>Single-trial evoked responses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lengle, J.M</creatorcontrib><creatorcontrib>Chen, M</creatorcontrib><creatorcontrib>Wakai, R.T</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical neurophysiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lengle, J.M</au><au>Chen, M</au><au>Wakai, R.T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Improved neuromagnetic detection of fetal and neonatal auditory evoked responses</atitle><jtitle>Clinical neurophysiology</jtitle><addtitle>Clin Neurophysiol</addtitle><date>2001-05-01</date><risdate>2001</risdate><volume>112</volume><issue>5</issue><spage>785</spage><epage>792</epage><pages>785-792</pages><issn>1388-2457</issn><eissn>1872-8952</eissn><abstract>Objective: To assess the quality of fetal and neonatal auditory evoked responses (fAERs and nAERs) obtainable with a low-noise, high-channel count SQUID gradiometer in a well-shielded environment.
Methods: Measurement of long-latency fAERs was attempted in 19 normal fetuses in 28 sessions at 29–40 weeks’ gestation, using a 37-channel SQUID gradiometer. Postnatal measurement was attempted in 16 neonates in 25 sessions at age 2–6 weeks.
Results: Signals of amplitude 8 fT or greater were detected in 15 of 28 fetal measurement sessions, yielding a higher success rate (54%) than in a previous study of ours. Signals of amplitude greater than 25 fT were detected in 23 of 25 (92%) of neonatal measurement sessions. The spatial and temporal characteristics of the signals were studied in greater detail. Dipole patterns consistent with a source in the auditory cortex were observable in nearly all neonates and in many fetuses. The dominant component of the nAER was compatible with the P250 seen in neonatal EEG recordings; however, the largest component of the fAERs had longer latency and in many subjects had opposite polarity.
Conclusion: A higher success rate, earlier detection, and improved characterization of signal morphology and topography were demonstrated for fAER recordings.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>11336893</pmid><doi>10.1016/S1388-2457(01)00532-6</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1388-2457 |
| ispartof | Clinical neurophysiology, 2001-05, Vol.112 (5), p.785-792 |
| issn | 1388-2457 1872-8952 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_70841796 |
| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Acoustic Stimulation Biological and medical sciences Brain - embryology Brain - physiology Electrodiagnosis. Electric activity recording Electroencephalography Evoked Potentials, Auditory - physiology Female Fetal auditory evoked responses Fetal brain activity Fetal magnetoencephalography Fetus - physiology Gestational Age Humans Infant Infant, Newborn - physiology Investigative techniques, diagnostic techniques (general aspects) Magnetoencephalography Medical sciences Neonatal brain activity Nervous system Pregnancy Reaction Time Single-trial evoked responses |
| title | Improved neuromagnetic detection of fetal and neonatal auditory evoked responses |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-12T21%3A38%3A32IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Improved%20neuromagnetic%20detection%20of%20fetal%20and%20neonatal%20auditory%20evoked%20responses&rft.jtitle=Clinical%20neurophysiology&rft.au=Lengle,%20J.M&rft.date=2001-05-01&rft.volume=112&rft.issue=5&rft.spage=785&rft.epage=792&rft.pages=785-792&rft.issn=1388-2457&rft.eissn=1872-8952&rft_id=info:doi/10.1016/S1388-2457(01)00532-6&rft_dat=%3Cproquest_cross%3E70841796%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=70841796&rft_id=info:pmid/11336893&rft_els_id=S1388245701005326&rfr_iscdi=true |