Clinical and microbial evaluation of a histatin-containing mouthrinse in humans with experimental gingivitis

Objective: P‐113, a 12 amino acid histatin‐based peptide, was evaluated in a mouthrinse formulation for safety, prevention of the development of experimental gingivitis, and for its effects on periodontal flora. Method: 159 periodontally healthy subjects abstained from oral hygiene procedures and se...

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Veröffentlicht in:	Journal of clinical periodontology 2001-05, Vol.28 (5), p.404-410
Hauptverfasser:	Mickels, Nancy, McManus, Colleen, Massaro, Joseph, Friden, Phillip, Braman, Virginia, D'Agostino, Ralph, Oppenheim, Frank, Warbington, Martha, Dibart, Serge, Van Dyke, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult antimicrobial mouthrinse Bacteria - classification Bacteria - drug effects clinical trial Dental Plaque - microbiology Dental Plaque - prevention & control Dental Plaque Index Dentistry Disease Progression Double-Blind Method Female Gingival Hemorrhage - prevention & control gingivitis Gingivitis - prevention & control Glycoproteins - administration & dosage Glycoproteins - therapeutic use histatin Histidine - administration & dosage Histidine - therapeutic use Humans Male Middle Aged Mouthwashes - therapeutic use Periodontal Index Periodontium - microbiology Placebos Prevotella intermedia - drug effects Proteins - administration & dosage Proteins - therapeutic use Safety Statistics as Topic supragingival plaque
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