Real-time multisite observation of glutamate release in rat hippocampal slices

A multichannel glutamate sensor was fabricated that consists of enzyme modified electrodes and has a high sensitivity and selectivity to glutamate. We placed a rat hippocampal slice on the sensor and monitored the current at four electrodes resulting from the stimulation with muscimol, a γ-aminobuty...

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Veröffentlicht in:	Neuroscience letters 2001-05, Vol.304 (1), p.112-116
Hauptverfasser:	Kasai, Nahoko, Jimbo, Yasuhiko, Niwa, Osamu, Matsue, Tomokazu, Torimitsu, Keiichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals bicuculline Bicuculline - pharmacology Biological and medical sciences Computer Systems Electrochemical detection Electrochemistry Electrode array Electrodes Fundamental and applied biological sciences. Psychology GABA Agonists - pharmacology GABA Antagonists - pharmacology General aspects. Models. Methods Glutamate Glutamate oxidase Glutamic Acid - drug effects Glutamic Acid - metabolism Hippocampus - drug effects Hippocampus - metabolism Horseradish peroxidase Muscimol - pharmacology Rats Vertebrates: nervous system and sense organs γ-aminobutyric acid
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