Sequence and organization of pXO1, the large Bacillus anthracis plasmid harboring the anthrax toxin genes

The Bacillus anthracis Sterne plasmid pXO1 was sequenced by random, "shotgun" cloning. A circular sequence of 181,654 bp was generated. One hundred forty-three open reading frames (ORFS) were predicted using GeneMark and GeneMark.hmm, comprising only 61% (110,817 bp) of the pXO1 DNA sequen...

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Veröffentlicht in:	Journal of Bacteriology 1999-10, Vol.181 (20), p.6509-6515
Hauptverfasser:	Okinaka, R.T, Cloud, K, Hampton, O, Hoffmaster, A.R, Hill, K.K, Keim, P, Koehler, T.M, Lamke, G, Kumano, S, Mahillon, J, Manter, D, Martinez, Y, Ricke, D, Svensson, R, Jackson, P.J
Format:	Artikel
Sprache:	eng
Schlagworte:	Anthrax anthrax lethal toxin Antigens, Bacterial Bacillus anthracis Bacillus anthracis - genetics Bacteria bacterial proteins bacterial toxins Bacterial Toxins - genetics Bacteriology cya gene Deoxyribonucleic acid DNA DNA, Bacterial - genetics Enzymes Experiments genbank/af065404 genes Genes, Bacterial identification insertion sequence IS1627 lef gene Molecular Sequence Data nucleotide sequences Open Reading Frames pagA gene pathogenicity islands plasmid pXO1 Plasmids - genetics Plasmids and Transposons Recombination, Genetic Replication Origin Restriction Mapping Sequence Analysis, DNA Sequence Homology Studies transposase
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