Ontogeny of P-Glycoprotein in Mouse Intestine, Liver, and Kidney

BackgroundP-glycoprotein (Pgp) is an ATP-dependent, integral plasma-membrane efflux pump that is constitutively expressed on (i) adult apical brush-border epithelial cells of the intestine, (ii) the bile canalicular face of hepatocytes, and (iii) the brush border epithelium of renal proximal tubules...

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Veröffentlicht in:	Journal of investigative medicine 2001-05, Vol.49 (3), p.250-257
Hauptverfasser:	Mahmood, Burhan, Daood, Monica J., Hart, Claudia, Hansen, Thor W.R., Watchko, Jon F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Animals Animals, Newborn ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism Blotting, Western Cell Fractionation Fluorescent Antibody Technique, Indirect Intestines - metabolism Intracellular Membranes - metabolism Kidney - metabolism Liver - metabolism Mice Microvilli - metabolism
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