Increased Soluble CD95 (sFas/CD95) Serum Level Correlates with Poor Prognosis in Melanoma Patients

Functional impairment of the Fas/CD95 receptor-ligand system is associated with the development and progression of malignancies. One possible cause might be the inhibition of the formation of a functional Fas/CD95-FasL complex by soluble Fas/CD95 molecules (sFas/CD95). In the present study we determ...

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Veröffentlicht in:	Clinical cancer research 2001-05, Vol.7 (5), p.1282-1286
Hauptverfasser:	UGUREL, Selma, RAPPL, Gunter, TILGEN, Wolfgang, REINHOLD, Uwe
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biomarkers, Tumor - blood Dermatology Disease Progression Disease-Free Survival fas Receptor - blood Female Humans Male Medical sciences Melanoma - blood Melanoma - diagnosis Melanoma - mortality Middle Aged Predictive Value of Tests Prognosis Survival Rate Tumors of the skin and soft tissue. Premalignant lesions
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