Limited adhesion of biodegradable microspheres to E- and P-selectin under flow

In a variety of disease settings the expression of the endothelial selectins E‐ and P‐selectin appears to be increased. This feature makes these molecules attractive targets around which to design directed drug‐delivery schemes. One possible approach for achieving such delivery is to use polymeric b...

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Veröffentlicht in:Biotechnology and bioengineering 2001-06, Vol.73 (6), p.500-509
Hauptverfasser: Dickerson, J. Bradley, Blackwell, Jonathan E., Ou, Jao J., Shinde Patil, Vivek R., Goetz, Douglas J.
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Sprache:eng
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