New Cytotoxic Polyacetylenes from the Marine Sponge Petrosia

New polyacetylenic alcohols with a C45 carbon skeleton (2) and with an enone moiety in the alkyl chain (C46, 1) were isolated from the marine sponge Petrosia sp. The gross structures of 1 and 2 were established by spectral methods, and the absolute stereochemistry was determined by the modified Mosh...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 1999-09, Vol.62 (9), p.1215-1217
Hauptverfasser:	Lim, Young Ja, Kim, Jung Sun, Im, Kwang Sik, Jung, Jee H, Lee, Chong-O, Hong, Jongki, Kim, Dong-kyoo
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylene - analogs & derivatives Acetylene - chemistry Acetylene - isolation & purification Acetylene - pharmacology Animals Antineoplastic Agents - chemistry Antineoplastic Agents - isolation & purification Antineoplastic Agents - pharmacology Biological and medical sciences DNA Replication - drug effects Drug Screening Assays, Antitumor General pharmacology Humans Marine Biology Medical sciences Molecular Structure Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Polymers - chemistry Polymers - isolation & purification Polymers - pharmacology Polyynes Porifera - chemistry Simian virus 40 - genetics Tumor Cells, Cultured
Online-Zugang:	Volltext
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