Effect of dexmedetomidine on the minimum alveolar concentration (MAC) of sevoflurane in adults age 55 to 70 years

Study Objective: To determine the effect of two target dexmedetomidine infusions (0.3 ng/ml and 0.6 ng/ml) on the minimal alveolar concentration (MAC) of sevoflurane in adults age 55 to 70 years. Design: Prospective, randomized, placebo-controlled study. Setting: University-affiliated hospital. Pati...

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Veröffentlicht in:	Journal of clinical anesthesia 1999-09, Vol.11 (6), p.466-470
Hauptverfasser:	Fragen, Robert J, Fitzgerald, Paul C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic alpha-Agonists - blood Adrenergic alpha-Agonists - pharmacology Aged Alpha-adrenergic agonist anesthesia, geriatric Anesthetics, Inhalation - metabolism Anesthetics, Inhalation - pharmacokinetics Dexmedetomidine - blood Dexmedetomidine - pharmacology dexmedetomidine, infusion of Female Humans Male Methyl Ethers - metabolism Methyl Ethers - pharmacokinetics Middle Aged Prospective Studies Pulmonary Alveoli - metabolism sevoflurane, minimum alveolar concentration
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