Serine Proteinase Inhibitor 3 and Murinoglobulin I Are Potent Inhibitors of Neuropsin in Adult Mouse Brain

Extracellular serine protease neuropsin (NP) is expressed in the forebrain limbic area of adult brain and is implicated in synaptic plasticity. We screened for endogenous NP inhibitors with recombinant NP (r-NP) from extracts of the hippocampus and the cerebral cortex in adult mouse brain. Two SDS-s...

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Veröffentlicht in:	The Journal of biological chemistry 2001-05, Vol.276 (18), p.14562-14571
Hauptverfasser:	Kato, Keiko, Kishi, Tadaaki, Kamachi, Tomohiro, Akisada, Morito, Oka, Takuya, Midorikawa, Ryosuke, Takio, Koji, Dohmae, Naoshi, Bird, Phillip I., Sun, Jiuru, Scott, Fiona, Miyake, Yoshimasa, Yamamoto, Kazuhiko, Machida, Atsunori, Tanaka, Tatsuya, Matsumoto, Kazumasa, Shibata, Masao, Shiosaka, Sadao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cerebral Cortex - drug effects Cerebral Cortex - enzymology Hippocampus - drug effects Hippocampus - enzymology Hydrolysis Kallikreins Mice Serine Endopeptidases - drug effects Serine Proteinase Inhibitors - pharmacology Serum Globulins - pharmacology
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