Diversity of core promoter mutations in immune clearance phase of chronic HBV infection

Transcription of HBV (hepatitis B virus) pre-core and pre-genomic mRNAs is controlled by core promoter. Therefore, mutations in the core promoter region might change the activity of liver diseases through an altered transcriptional level of the mRNA. The present study was carried out to determine th...

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Veröffentlicht in:	European journal of gastroenterology & hepatology 1999-08, Vol.11 (8), p.821-826
Hauptverfasser:	Kim, Yun Soo, Kim, Sung II, Hwang, Seong Gyu, Kim, Jin Oh, Cho, Joo Young, Lee, Joon Seong, Lee, Moon Sung, Hwang, Seung Duk, Shim, Chan Sup
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Base Sequence Biological and medical sciences Carrier State - immunology Carrier State - virology Child DNA Mutational Analysis DNA, Viral - genetics Female Hepatitis B Antibodies - blood Hepatitis B e Antigens - blood Hepatitis B virus - genetics Hepatitis B virus - isolation & purification Hepatitis B, Chronic - immunology Hepatitis B, Chronic - virology Human viral diseases Humans Infectious diseases Male Medical sciences Middle Aged Molecular Sequence Data Mutation Polymerase Chain Reaction Promoter Regions, Genetic - genetics Tropical medicine Viral Core Proteins - genetics Viral diseases Viral hepatitis
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