A feasible method for clinical delivery verification and dose reconstruction in tomotherapy
Delivery verification is the process in which the energy fluence delivered during a treatment is verified. This verified energy fluence can be used in conjunction with an image in the treatment position to reconstruct the full three-dimensional dose deposited. A method for delivery verification that...
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| Veröffentlicht in: | Medical physics (Lancaster) 2001-04, Vol.28 (4), p.528-542 |
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| creator | Kapatoes, J. M. Olivera, G. H. Ruchala, K. J. Smilowitz, J. B. Reckwerdt, P. J. Mackie, T. R. |
| description | Delivery verification is the process in which the energy fluence delivered during a treatment is verified. This verified energy fluence can be used in conjunction with an image in the treatment position to reconstruct the full three-dimensional dose deposited. A method for delivery verification that utilizes a measured database of detector signal is described in this work. This database is a function of two parameters, radiological path-length and detector-to-phantom distance, both of which are computed from a CT image taken at the time of delivery. Such a database was generated and used to perform delivery verification and dose reconstruction. Two experiments were conducted: a simulated prostate delivery on an inhomogeneous abdominal phantom, and a nasopharyngeal delivery on a dog cadaver. For both cases, it was found that the verified fluence and dose results using the database approach agreed very well with those using previously developed and proven techniques. Delivery verification with a measured database and CT image at the time of treatment is an accurate procedure for tomotherapy. The database eliminates the need for any patient-specific, pre- or post-treatment measurements. Moreover, such an approach creates an opportunity for accurate, real-time delivery verification and dose reconstruction given fast image reconstruction and dose computation tools. |
| doi_str_mv | 10.1118/1.1352579 |
| format | Article |
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Two experiments were conducted: a simulated prostate delivery on an inhomogeneous abdominal phantom, and a nasopharyngeal delivery on a dog cadaver. For both cases, it was found that the verified fluence and dose results using the database approach agreed very well with those using previously developed and proven techniques. Delivery verification with a measured database and CT image at the time of treatment is an accurate procedure for tomotherapy. The database eliminates the need for any patient-specific, pre- or post-treatment measurements. Moreover, such an approach creates an opportunity for accurate, real-time delivery verification and dose reconstruction given fast image reconstruction and dose computation tools.</description><identifier>ISSN: 0094-2405</identifier><identifier>EISSN: 2473-4209</identifier><identifier>DOI: 10.1118/1.1352579</identifier><identifier>PMID: 11339750</identifier><identifier>CODEN: MPHYA6</identifier><language>eng</language><publisher>United States: American Association of Physicists in Medicine</publisher><subject>Animals ; Computed tomography ; Databases, Factual ; delivery verification ; Dogs ; dose reconstruction ; dosimetry ; Dosimetry/exposure assessment ; Drug delivery ; Energy delivery ; Humans ; Image sensors ; Male ; Medical image reconstruction ; Medical imaging ; Models, Statistical ; Nasopharynx - pathology ; Phantoms, Imaging ; Physicists ; Prostate - pathology ; radiation therapy ; Radiometry - methods ; Radiotherapy, Conformal - methods ; Real time information delivery ; Tomography, X-Ray Computed - instrumentation ; Tomography, X-Ray Computed - methods ; tomotherapy</subject><ispartof>Medical physics (Lancaster), 2001-04, Vol.28 (4), p.528-542</ispartof><rights>American Association of Physicists in Medicine</rights><rights>2001 American Association of Physicists in Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4909-7418ec3122198282a4ec632f4ebc88f3e9ee78bb96fd51861d85f7d9411b87133</citedby><cites>FETCH-LOGICAL-c4909-7418ec3122198282a4ec632f4ebc88f3e9ee78bb96fd51861d85f7d9411b87133</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1118%2F1.1352579$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1118%2F1.1352579$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11339750$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kapatoes, J. M.</creatorcontrib><creatorcontrib>Olivera, G. H.</creatorcontrib><creatorcontrib>Ruchala, K. J.</creatorcontrib><creatorcontrib>Smilowitz, J. B.</creatorcontrib><creatorcontrib>Reckwerdt, P. J.</creatorcontrib><creatorcontrib>Mackie, T. R.</creatorcontrib><title>A feasible method for clinical delivery verification and dose reconstruction in tomotherapy</title><title>Medical physics (Lancaster)</title><addtitle>Med Phys</addtitle><description>Delivery verification is the process in which the energy fluence delivered during a treatment is verified. This verified energy fluence can be used in conjunction with an image in the treatment position to reconstruct the full three-dimensional dose deposited. A method for delivery verification that utilizes a measured database of detector signal is described in this work. This database is a function of two parameters, radiological path-length and detector-to-phantom distance, both of which are computed from a CT image taken at the time of delivery. Such a database was generated and used to perform delivery verification and dose reconstruction. Two experiments were conducted: a simulated prostate delivery on an inhomogeneous abdominal phantom, and a nasopharyngeal delivery on a dog cadaver. For both cases, it was found that the verified fluence and dose results using the database approach agreed very well with those using previously developed and proven techniques. Delivery verification with a measured database and CT image at the time of treatment is an accurate procedure for tomotherapy. The database eliminates the need for any patient-specific, pre- or post-treatment measurements. Moreover, such an approach creates an opportunity for accurate, real-time delivery verification and dose reconstruction given fast image reconstruction and dose computation tools.</description><subject>Animals</subject><subject>Computed tomography</subject><subject>Databases, Factual</subject><subject>delivery verification</subject><subject>Dogs</subject><subject>dose reconstruction</subject><subject>dosimetry</subject><subject>Dosimetry/exposure assessment</subject><subject>Drug delivery</subject><subject>Energy delivery</subject><subject>Humans</subject><subject>Image sensors</subject><subject>Male</subject><subject>Medical image reconstruction</subject><subject>Medical imaging</subject><subject>Models, Statistical</subject><subject>Nasopharynx - pathology</subject><subject>Phantoms, Imaging</subject><subject>Physicists</subject><subject>Prostate - pathology</subject><subject>radiation therapy</subject><subject>Radiometry - methods</subject><subject>Radiotherapy, Conformal - methods</subject><subject>Real time information delivery</subject><subject>Tomography, X-Ray Computed - instrumentation</subject><subject>Tomography, X-Ray Computed - methods</subject><subject>tomotherapy</subject><issn>0094-2405</issn><issn>2473-4209</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1r3DAQhkVpSLZJDv0DRadCC041-rCl47I0aWBDckhOORhbGhEV29pK3g377-NmDe0luczAy8MzzEvIZ2AXAKB_wAUIxVVlPpAFl5UoJGfmI1kwZmTBJVMn5FPOvxljpVDsmJwACGEqxRbkcUk9Njm0HdIex6foqI-J2i4MwTYdddiFHaY9nUbwUzSGONBmcNTFjDShjUMe09a-5mGgY-zj-ISp2ezPyJFvuozn8z4lD5c_71e_ivXt1fVquS6sNMwUlQSNVgDnYDTXvJFoS8G9xNZq7QUaxEq3rSm9U6BLcFr5yhkJ0Opq-uSUfD14Nyn-2WIe6z5ki13XDBi3ua6YhlIpNYHfDqBNMeeEvt6k0DdpXwOr_zZZQz03ObFfZum27dH9I-fqJqA4AM-hw_3bpvrmbhZ-P_DZhvG1xnevvwnvYvpPvnFevAA7V5fe</recordid><startdate>200104</startdate><enddate>200104</enddate><creator>Kapatoes, J. M.</creator><creator>Olivera, G. H.</creator><creator>Ruchala, K. J.</creator><creator>Smilowitz, J. B.</creator><creator>Reckwerdt, P. J.</creator><creator>Mackie, T. R.</creator><general>American Association of Physicists in Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200104</creationdate><title>A feasible method for clinical delivery verification and dose reconstruction in tomotherapy</title><author>Kapatoes, J. M. ; Olivera, G. H. ; Ruchala, K. J. ; Smilowitz, J. B. ; Reckwerdt, P. J. ; Mackie, T. R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4909-7418ec3122198282a4ec632f4ebc88f3e9ee78bb96fd51861d85f7d9411b87133</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Animals</topic><topic>Computed tomography</topic><topic>Databases, Factual</topic><topic>delivery verification</topic><topic>Dogs</topic><topic>dose reconstruction</topic><topic>dosimetry</topic><topic>Dosimetry/exposure assessment</topic><topic>Drug delivery</topic><topic>Energy delivery</topic><topic>Humans</topic><topic>Image sensors</topic><topic>Male</topic><topic>Medical image reconstruction</topic><topic>Medical imaging</topic><topic>Models, Statistical</topic><topic>Nasopharynx - pathology</topic><topic>Phantoms, Imaging</topic><topic>Physicists</topic><topic>Prostate - pathology</topic><topic>radiation therapy</topic><topic>Radiometry - methods</topic><topic>Radiotherapy, Conformal - methods</topic><topic>Real time information delivery</topic><topic>Tomography, X-Ray Computed - instrumentation</topic><topic>Tomography, X-Ray Computed - methods</topic><topic>tomotherapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kapatoes, J. M.</creatorcontrib><creatorcontrib>Olivera, G. H.</creatorcontrib><creatorcontrib>Ruchala, K. J.</creatorcontrib><creatorcontrib>Smilowitz, J. B.</creatorcontrib><creatorcontrib>Reckwerdt, P. J.</creatorcontrib><creatorcontrib>Mackie, T. R.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Medical physics (Lancaster)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kapatoes, J. M.</au><au>Olivera, G. H.</au><au>Ruchala, K. J.</au><au>Smilowitz, J. B.</au><au>Reckwerdt, P. J.</au><au>Mackie, T. R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A feasible method for clinical delivery verification and dose reconstruction in tomotherapy</atitle><jtitle>Medical physics (Lancaster)</jtitle><addtitle>Med Phys</addtitle><date>2001-04</date><risdate>2001</risdate><volume>28</volume><issue>4</issue><spage>528</spage><epage>542</epage><pages>528-542</pages><issn>0094-2405</issn><eissn>2473-4209</eissn><coden>MPHYA6</coden><abstract>Delivery verification is the process in which the energy fluence delivered during a treatment is verified. This verified energy fluence can be used in conjunction with an image in the treatment position to reconstruct the full three-dimensional dose deposited. A method for delivery verification that utilizes a measured database of detector signal is described in this work. This database is a function of two parameters, radiological path-length and detector-to-phantom distance, both of which are computed from a CT image taken at the time of delivery. Such a database was generated and used to perform delivery verification and dose reconstruction. Two experiments were conducted: a simulated prostate delivery on an inhomogeneous abdominal phantom, and a nasopharyngeal delivery on a dog cadaver. For both cases, it was found that the verified fluence and dose results using the database approach agreed very well with those using previously developed and proven techniques. Delivery verification with a measured database and CT image at the time of treatment is an accurate procedure for tomotherapy. The database eliminates the need for any patient-specific, pre- or post-treatment measurements. Moreover, such an approach creates an opportunity for accurate, real-time delivery verification and dose reconstruction given fast image reconstruction and dose computation tools.</abstract><cop>United States</cop><pub>American Association of Physicists in Medicine</pub><pmid>11339750</pmid><doi>10.1118/1.1352579</doi><tpages>15</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Animals Computed tomography Databases, Factual delivery verification Dogs dose reconstruction dosimetry Dosimetry/exposure assessment Drug delivery Energy delivery Humans Image sensors Male Medical image reconstruction Medical imaging Models, Statistical Nasopharynx - pathology Phantoms, Imaging Physicists Prostate - pathology radiation therapy Radiometry - methods Radiotherapy, Conformal - methods Real time information delivery Tomography, X-Ray Computed - instrumentation Tomography, X-Ray Computed - methods tomotherapy |
| title | A feasible method for clinical delivery verification and dose reconstruction in tomotherapy |
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