Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans

To examine the efficacy of Lactobacillus gasseri OLL2716 (LG21) as a probiotic for Helicobacter pylori in humans, 31 subjects infected with the bacterium ingested yogurt containing LG21 daily for an 8 week period. The [13C]urea breath test and assays of serum pepsinogens revealed a significant impro...

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Veröffentlicht in:Journal of antimicrobial chemotherapy 2001-05, Vol.47 (5), p.709-710
Hauptverfasser: Sakamoto, Ichiko, Igarashi, Muneki, Kimura, Katsunori, Takagi, Atsushi, Miwa, Takeshi, Koga, Yasuhiro
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Sprache:eng
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Zusammenfassung:To examine the efficacy of Lactobacillus gasseri OLL2716 (LG21) as a probiotic for Helicobacter pylori in humans, 31 subjects infected with the bacterium ingested yogurt containing LG21 daily for an 8 week period. The [13C]urea breath test and assays of serum pepsinogens revealed a significant improvement following LG21 treatment. LG21 was thus determined to be effective in both suppressing H. pylori and reducing gastric mucosal inflammation.
ISSN:0305-7453
1460-2091
DOI:10.1093/jac/47.5.709