Increased Glutathionyl Hemoglobin in Diabetes Mellitus and Hyperlipidemia Demonstrated by Liquid Chromatography/Electrospray Ionization-Mass Spectrometry

Erythrocytes contain a large amount of glutathione (GSH), which protects cells from oxidative injury. The purpose of this study was to examine whether hemoglobin (Hb) is modified with glutathione by oxidation of the thiol groups in diabetes mellitus and hyperlipidemia, and to determine the oxygen af...

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Veröffentlicht in:	Clinical chemistry (Baltimore, Md.) Md.), 2000-01, Vol.46 (1), p.82-88
Hauptverfasser:	Niwa, Toshimitsu, Naito, Chika, Mawjood, Abdul Hassan Mohammed, Imai, Kiyohiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Biological and medical sciences Chromatography, Liquid Diabetes Mellitus - blood Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Female Fundamental and applied biological sciences. Psychology Glutathione - chemistry Glutathione - metabolism Hemoglobins - chemistry Hemoglobins - metabolism Hemoproteins Humans Hyperlipidemias - blood Male Management. Various non-drug treatments. Langerhans islet grafts Mass Spectrometry Medical sciences Metalloproteins Oxygen - chemistry Proteins
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