Abnormal ornithine decarboxylase activity in transgenic mice increases tumor formation and infertility

A transgenic mouse line carrying ornithine decarboxylase cDNA as the transgene under the control of a mouse mammary tumor virus long terminal repeat (MMTV LTR) promoter was generated in order to study whether ornithine decarboxylase transgene expression will have any physiological or pathological ef...

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Veröffentlicht in:	The international journal of biochemistry & cell biology 2001-05, Vol.33 (5), p.507-520
Hauptverfasser:	Kilpeläinen, P.T., Saarimies, J., Kontusaari, S.I., Järvinen, M.J., Soler, A.Peralta, Kallioinen, M.J., Hietala, O.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Female Genitalia, Male - anatomy & histology Genitalia, Male - enzymology Heterozygote Infertility - etiology Male Mice Mice, Transgenic Neoplasms - enzymology Neoplasms - etiology Ornithine decarboxylase Ornithine Decarboxylase - genetics Ornithine Decarboxylase - metabolism Promoter Regions, Genetic Transgenic mouse line Tumors
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