Muc1 and Glycan Expression in the Oviduct and Endometrium of a New World Monkey, Cebus apella
Cebus apella is a New World monkey that has a menstrual cycle of 18â23 days with implantation at approximately luteal Day 5. The aim of this study was to characterize by lectin- and antibody-labeling the distribution of Muc1 and associated glycans on the endometrial and oviductal epithelium during...
Gespeichert in:
| Veröffentlicht in: | Biology of reproduction 2001-05, Vol.64 (5), p.1535-1544 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1544 |
|---|---|
| container_issue | 5 |
| container_start_page | 1535 |
| container_title | Biology of reproduction |
| container_volume | 64 |
| creator | JONES, Carolyn J. P ORTIZ, Maria Elena CROXATTO, Horacio B MANZUR, Alejandro SLEVIN, Geraldine APLIN, John D |
| description | Cebus apella is a New World monkey that has a menstrual cycle of 18â23 days with implantation at approximately luteal Day 5. The aim of
this study was to characterize by lectin- and antibody-labeling the distribution of Muc1 and associated glycans on the endometrial
and oviductal epithelium during the luteal phase of the cycle. Endometrial histology showed a thin endometrium, with glands
extending deeply into the myometrium. No obvious evidence of secretory differentiation in cells of either the superficial
or the basal segments of glands could be obtained using a panel of antibodies and lectins that marked epithelial glycoprotein,
and glycosylation changes observed in some other primate endometrial cycles were not observed in this study. Antibodies to
human MUC1 were shown to cross-react with C. apella , and Muc1 was localized to the apical epithelial surfaces of both the endometrial and the tubal epithelium, with stronger
expression in the latter. Again, no cyclic changes were noted. Antibodies specific to the isoform Muc1/Sec showed strong staining
at the apical tubal epithelium, but no reactivity was detectable in the luminal epithelium of the uterus. This observation
suggests differences between the two glycocalyces and could help to explain why C. apella embryos do not implant in this location. |
| doi_str_mv | 10.1095/biolreprod64.5.1535 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_70804276</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>70804276</sourcerecordid><originalsourceid>FETCH-LOGICAL-h267t-99d322d0140dfa3abca8ce74d993c80b80b62a4bf3b64aed1c142e5a8b7b96603</originalsourceid><addsrcrecordid>eNpFkUtLw0AUhQdRtFZ_gSCzEFemziOZJEsp9QGtbhRXEu48YkcnSZ1JjP33Rq0UDpzNx7mHcxE6oWRCSZ5cSts4b1a-0SKeJBOa8GQHjWjC8ihlIttFI0KIiDgX_AAdhvBGCI054_vogFJOcyrYCL0sOkUx1BrfuLWCGs--Vt6EYJsa2xq3S4MfPq3uVPsLzWrdVKb1tqtwU2LA96bHz413Gi-a-t2sL_DUyC5gWBnn4AjtleCCOd74GD1dzx6nt9H84eZuejWPlkykbZTnmjOmh3pEl8BBKsiUSWOd51xlRA4SDGJZciliMJoqGjOTQCZTmQtB-Bid_-UOa3x0JrRFZYP6aVCbpgtFSjISs1QM4OkG7GRldLHytgK_Lv4HGYCzDQBBgSs91MqGLUfSTCTZ9uDSvi57600RKnBuSOVF3_ciLpLi5yH8G5fhfjw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>70804276</pqid></control><display><type>article</type><title>Muc1 and Glycan Expression in the Oviduct and Endometrium of a New World Monkey, Cebus apella</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>BioOne Complete</source><source>Oxford University Press Journals All Titles (1996-Current)</source><creator>JONES, Carolyn J. P ; ORTIZ, Maria Elena ; CROXATTO, Horacio B ; MANZUR, Alejandro ; SLEVIN, Geraldine ; APLIN, John D</creator><creatorcontrib>JONES, Carolyn J. P ; ORTIZ, Maria Elena ; CROXATTO, Horacio B ; MANZUR, Alejandro ; SLEVIN, Geraldine ; APLIN, John D</creatorcontrib><description>Cebus apella is a New World monkey that has a menstrual cycle of 18â23 days with implantation at approximately luteal Day 5. The aim of
this study was to characterize by lectin- and antibody-labeling the distribution of Muc1 and associated glycans on the endometrial
and oviductal epithelium during the luteal phase of the cycle. Endometrial histology showed a thin endometrium, with glands
extending deeply into the myometrium. No obvious evidence of secretory differentiation in cells of either the superficial
or the basal segments of glands could be obtained using a panel of antibodies and lectins that marked epithelial glycoprotein,
and glycosylation changes observed in some other primate endometrial cycles were not observed in this study. Antibodies to
human MUC1 were shown to cross-react with C. apella , and Muc1 was localized to the apical epithelial surfaces of both the endometrial and the tubal epithelium, with stronger
expression in the latter. Again, no cyclic changes were noted. Antibodies specific to the isoform Muc1/Sec showed strong staining
at the apical tubal epithelium, but no reactivity was detectable in the luminal epithelium of the uterus. This observation
suggests differences between the two glycocalyces and could help to explain why C. apella embryos do not implant in this location.</description><identifier>ISSN: 0006-3363</identifier><identifier>EISSN: 1529-7268</identifier><identifier>DOI: 10.1095/biolreprod64.5.1535</identifier><identifier>PMID: 11319162</identifier><identifier>CODEN: BIREBV</identifier><language>eng</language><publisher>Madison, WI: Society for the Study of Reproduction</publisher><subject>Animals ; Antibody Specificity ; Biological and medical sciences ; Cebus ; Endometrium - chemistry ; Epithelial Cells - chemistry ; Epithelium - chemistry ; Fallopian Tubes - chemistry ; Female ; Fluorescent Antibody Technique ; Fundamental and applied biological sciences. Psychology ; Glycosylation ; Histocytochemistry ; Humans ; Immunohistochemistry ; Lectins - analysis ; Mammalian female genital system ; Morphology. Physiology ; Mucin-1 - analysis ; Neuraminidase - pharmacology ; Polysaccharides - analysis ; Vertebrates: reproduction</subject><ispartof>Biology of reproduction, 2001-05, Vol.64 (5), p.1535-1544</ispartof><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1078658$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11319162$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>JONES, Carolyn J. P</creatorcontrib><creatorcontrib>ORTIZ, Maria Elena</creatorcontrib><creatorcontrib>CROXATTO, Horacio B</creatorcontrib><creatorcontrib>MANZUR, Alejandro</creatorcontrib><creatorcontrib>SLEVIN, Geraldine</creatorcontrib><creatorcontrib>APLIN, John D</creatorcontrib><title>Muc1 and Glycan Expression in the Oviduct and Endometrium of a New World Monkey, Cebus apella</title><title>Biology of reproduction</title><addtitle>Biol Reprod</addtitle><description>Cebus apella is a New World monkey that has a menstrual cycle of 18â23 days with implantation at approximately luteal Day 5. The aim of
this study was to characterize by lectin- and antibody-labeling the distribution of Muc1 and associated glycans on the endometrial
and oviductal epithelium during the luteal phase of the cycle. Endometrial histology showed a thin endometrium, with glands
extending deeply into the myometrium. No obvious evidence of secretory differentiation in cells of either the superficial
or the basal segments of glands could be obtained using a panel of antibodies and lectins that marked epithelial glycoprotein,
and glycosylation changes observed in some other primate endometrial cycles were not observed in this study. Antibodies to
human MUC1 were shown to cross-react with C. apella , and Muc1 was localized to the apical epithelial surfaces of both the endometrial and the tubal epithelium, with stronger
expression in the latter. Again, no cyclic changes were noted. Antibodies specific to the isoform Muc1/Sec showed strong staining
at the apical tubal epithelium, but no reactivity was detectable in the luminal epithelium of the uterus. This observation
suggests differences between the two glycocalyces and could help to explain why C. apella embryos do not implant in this location.</description><subject>Animals</subject><subject>Antibody Specificity</subject><subject>Biological and medical sciences</subject><subject>Cebus</subject><subject>Endometrium - chemistry</subject><subject>Epithelial Cells - chemistry</subject><subject>Epithelium - chemistry</subject><subject>Fallopian Tubes - chemistry</subject><subject>Female</subject><subject>Fluorescent Antibody Technique</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Glycosylation</subject><subject>Histocytochemistry</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><subject>Lectins - analysis</subject><subject>Mammalian female genital system</subject><subject>Morphology. Physiology</subject><subject>Mucin-1 - analysis</subject><subject>Neuraminidase - pharmacology</subject><subject>Polysaccharides - analysis</subject><subject>Vertebrates: reproduction</subject><issn>0006-3363</issn><issn>1529-7268</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkUtLw0AUhQdRtFZ_gSCzEFemziOZJEsp9QGtbhRXEu48YkcnSZ1JjP33Rq0UDpzNx7mHcxE6oWRCSZ5cSts4b1a-0SKeJBOa8GQHjWjC8ihlIttFI0KIiDgX_AAdhvBGCI054_vogFJOcyrYCL0sOkUx1BrfuLWCGs--Vt6EYJsa2xq3S4MfPq3uVPsLzWrdVKb1tqtwU2LA96bHz413Gi-a-t2sL_DUyC5gWBnn4AjtleCCOd74GD1dzx6nt9H84eZuejWPlkykbZTnmjOmh3pEl8BBKsiUSWOd51xlRA4SDGJZciliMJoqGjOTQCZTmQtB-Bid_-UOa3x0JrRFZYP6aVCbpgtFSjISs1QM4OkG7GRldLHytgK_Lv4HGYCzDQBBgSs91MqGLUfSTCTZ9uDSvi57600RKnBuSOVF3_ciLpLi5yH8G5fhfjw</recordid><startdate>20010501</startdate><enddate>20010501</enddate><creator>JONES, Carolyn J. P</creator><creator>ORTIZ, Maria Elena</creator><creator>CROXATTO, Horacio B</creator><creator>MANZUR, Alejandro</creator><creator>SLEVIN, Geraldine</creator><creator>APLIN, John D</creator><general>Society for the Study of Reproduction</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20010501</creationdate><title>Muc1 and Glycan Expression in the Oviduct and Endometrium of a New World Monkey, Cebus apella</title><author>JONES, Carolyn J. P ; ORTIZ, Maria Elena ; CROXATTO, Horacio B ; MANZUR, Alejandro ; SLEVIN, Geraldine ; APLIN, John D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h267t-99d322d0140dfa3abca8ce74d993c80b80b62a4bf3b64aed1c142e5a8b7b96603</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Animals</topic><topic>Antibody Specificity</topic><topic>Biological and medical sciences</topic><topic>Cebus</topic><topic>Endometrium - chemistry</topic><topic>Epithelial Cells - chemistry</topic><topic>Epithelium - chemistry</topic><topic>Fallopian Tubes - chemistry</topic><topic>Female</topic><topic>Fluorescent Antibody Technique</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Glycosylation</topic><topic>Histocytochemistry</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><topic>Lectins - analysis</topic><topic>Mammalian female genital system</topic><topic>Morphology. Physiology</topic><topic>Mucin-1 - analysis</topic><topic>Neuraminidase - pharmacology</topic><topic>Polysaccharides - analysis</topic><topic>Vertebrates: reproduction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>JONES, Carolyn J. P</creatorcontrib><creatorcontrib>ORTIZ, Maria Elena</creatorcontrib><creatorcontrib>CROXATTO, Horacio B</creatorcontrib><creatorcontrib>MANZUR, Alejandro</creatorcontrib><creatorcontrib>SLEVIN, Geraldine</creatorcontrib><creatorcontrib>APLIN, John D</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Biology of reproduction</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>JONES, Carolyn J. P</au><au>ORTIZ, Maria Elena</au><au>CROXATTO, Horacio B</au><au>MANZUR, Alejandro</au><au>SLEVIN, Geraldine</au><au>APLIN, John D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Muc1 and Glycan Expression in the Oviduct and Endometrium of a New World Monkey, Cebus apella</atitle><jtitle>Biology of reproduction</jtitle><addtitle>Biol Reprod</addtitle><date>2001-05-01</date><risdate>2001</risdate><volume>64</volume><issue>5</issue><spage>1535</spage><epage>1544</epage><pages>1535-1544</pages><issn>0006-3363</issn><eissn>1529-7268</eissn><coden>BIREBV</coden><abstract>Cebus apella is a New World monkey that has a menstrual cycle of 18â23 days with implantation at approximately luteal Day 5. The aim of
this study was to characterize by lectin- and antibody-labeling the distribution of Muc1 and associated glycans on the endometrial
and oviductal epithelium during the luteal phase of the cycle. Endometrial histology showed a thin endometrium, with glands
extending deeply into the myometrium. No obvious evidence of secretory differentiation in cells of either the superficial
or the basal segments of glands could be obtained using a panel of antibodies and lectins that marked epithelial glycoprotein,
and glycosylation changes observed in some other primate endometrial cycles were not observed in this study. Antibodies to
human MUC1 were shown to cross-react with C. apella , and Muc1 was localized to the apical epithelial surfaces of both the endometrial and the tubal epithelium, with stronger
expression in the latter. Again, no cyclic changes were noted. Antibodies specific to the isoform Muc1/Sec showed strong staining
at the apical tubal epithelium, but no reactivity was detectable in the luminal epithelium of the uterus. This observation
suggests differences between the two glycocalyces and could help to explain why C. apella embryos do not implant in this location.</abstract><cop>Madison, WI</cop><pub>Society for the Study of Reproduction</pub><pmid>11319162</pmid><doi>10.1095/biolreprod64.5.1535</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0006-3363 |
| ispartof | Biology of reproduction, 2001-05, Vol.64 (5), p.1535-1544 |
| issn | 0006-3363 1529-7268 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_70804276 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; BioOne Complete; Oxford University Press Journals All Titles (1996-Current) |
| subjects | Animals Antibody Specificity Biological and medical sciences Cebus Endometrium - chemistry Epithelial Cells - chemistry Epithelium - chemistry Fallopian Tubes - chemistry Female Fluorescent Antibody Technique Fundamental and applied biological sciences. Psychology Glycosylation Histocytochemistry Humans Immunohistochemistry Lectins - analysis Mammalian female genital system Morphology. Physiology Mucin-1 - analysis Neuraminidase - pharmacology Polysaccharides - analysis Vertebrates: reproduction |
| title | Muc1 and Glycan Expression in the Oviduct and Endometrium of a New World Monkey, Cebus apella |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T18%3A54%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Muc1%20and%20Glycan%20Expression%20in%20the%20Oviduct%20and%20Endometrium%20of%20a%20New%20World%20Monkey,%20Cebus%20apella&rft.jtitle=Biology%20of%20reproduction&rft.au=JONES,%20Carolyn%20J.%20P&rft.date=2001-05-01&rft.volume=64&rft.issue=5&rft.spage=1535&rft.epage=1544&rft.pages=1535-1544&rft.issn=0006-3363&rft.eissn=1529-7268&rft.coden=BIREBV&rft_id=info:doi/10.1095/biolreprod64.5.1535&rft_dat=%3Cproquest_pubme%3E70804276%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=70804276&rft_id=info:pmid/11319162&rfr_iscdi=true |