Polynesians: prone to obesity and Type 2 diabetes mellitus but not hyperinsulinaemia
SUMMARY Aims To compare the extent of hyperinsulinaemia among New Zealand Europeans and Polynesians (an ethnic group at high risk of Type 2 diabetes mellitus). Methods A cross‐sectional survey from randomly selected households was conducted in inner urban South Auckland. Subjects were either Euro...
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| Veröffentlicht in: | Diabetic medicine 2001-03, Vol.18 (3), p.193-198 |
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| creator | Simmons, D. Thompson, C. F. Volklander, D. |
| description | SUMMARY
Aims To compare the extent of hyperinsulinaemia among New Zealand Europeans and Polynesians (an ethnic group at high risk of Type 2 diabetes mellitus).
Methods A cross‐sectional survey from randomly selected households was conducted in inner urban South Auckland.
Subjects were either European, Maori or Pacific Islands Polynesians aged 40–79 years and were screened for diabetes using a random blood glucose. Those with an elevated result, and 20% randomly selected from those with a normal screening result, were invited to a 75‐g glucose tolerance test. WHO criteria (1998) for diabetes were used
Results In those aged 40–59 years, total prevalence of diabetes was 7.5 (6.2–9.0)% in Europeans but 21.1 (16.6–25.6)% among Maori and 25.0 (19.8–30.1)% among Pacific peoples; obesity (body mass index ≥ 31.0 kg/m2) was present in 26% Europeans, 63% Maori and 69% Pacific peoples. Non‐diabetic Polynesians were relatively hyperglycaemic and hyperinsulinaemic. After adjusting for the degree of obesity, Polynesians had similar insulin levels to Europeans.
Conclusions These findings indicate that Polynesians are not intrinsically insulin resistant as a group, a prerequisite found in most other ethnic groups at high risk of Type 2 diabetes mellitus. The high prevalence of Type 2 diabetes in Polynesians could be the result of their high prevalence of obesity. |
| doi_str_mv | 10.1046/j.1464-5491.2001.00435.x |
| format | Article |
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Aims To compare the extent of hyperinsulinaemia among New Zealand Europeans and Polynesians (an ethnic group at high risk of Type 2 diabetes mellitus).
Methods A cross‐sectional survey from randomly selected households was conducted in inner urban South Auckland.
Subjects were either European, Maori or Pacific Islands Polynesians aged 40–79 years and were screened for diabetes using a random blood glucose. Those with an elevated result, and 20% randomly selected from those with a normal screening result, were invited to a 75‐g glucose tolerance test. WHO criteria (1998) for diabetes were used
Results In those aged 40–59 years, total prevalence of diabetes was 7.5 (6.2–9.0)% in Europeans but 21.1 (16.6–25.6)% among Maori and 25.0 (19.8–30.1)% among Pacific peoples; obesity (body mass index ≥ 31.0 kg/m2) was present in 26% Europeans, 63% Maori and 69% Pacific peoples. Non‐diabetic Polynesians were relatively hyperglycaemic and hyperinsulinaemic. After adjusting for the degree of obesity, Polynesians had similar insulin levels to Europeans.
Conclusions These findings indicate that Polynesians are not intrinsically insulin resistant as a group, a prerequisite found in most other ethnic groups at high risk of Type 2 diabetes mellitus. The high prevalence of Type 2 diabetes in Polynesians could be the result of their high prevalence of obesity.</description><identifier>ISSN: 0742-3071</identifier><identifier>EISSN: 1464-5491</identifier><identifier>DOI: 10.1046/j.1464-5491.2001.00435.x</identifier><identifier>PMID: 11318839</identifier><identifier>CODEN: DIMEEV</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Science Ltd</publisher><subject>Adult ; Aged ; Australia - epidemiology ; Biological and medical sciences ; Blood Glucose - analysis ; Diabetes Mellitus, Type 2 - epidemiology ; Diabetes. Impaired glucose tolerance ; Endocrine pancreas. Apud cells (diseases) ; Endocrinopathies ; Ethnic Groups ; Etiopathogenesis. Screening. Investigations. Target tissue resistance ; Europe - ethnology ; European Continental Ancestry Group ; Female ; glucose ; Humans ; Hyperglycemia - epidemiology ; Hyperinsulinism - epidemiology ; insulin ; Insulin - blood ; Insulin Resistance ; Male ; Mass Screening ; Medical sciences ; Middle Aged ; New Zealand - epidemiology ; obesity ; Obesity - epidemiology ; Polynesia - ethnology ; Polynesian ; Type 2 diabetes mellitus ; Urban Population - statistics & numerical data</subject><ispartof>Diabetic medicine, 2001-03, Vol.18 (3), p.193-198</ispartof><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4805-eaece773ebae5136664d5ebef36b90107d24dcca3196340a27425a3bbeb360633</citedby><cites>FETCH-LOGICAL-c4805-eaece773ebae5136664d5ebef36b90107d24dcca3196340a27425a3bbeb360633</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1046%2Fj.1464-5491.2001.00435.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1046%2Fj.1464-5491.2001.00435.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=972493$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11318839$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Simmons, D.</creatorcontrib><creatorcontrib>Thompson, C. F.</creatorcontrib><creatorcontrib>Volklander, D.</creatorcontrib><title>Polynesians: prone to obesity and Type 2 diabetes mellitus but not hyperinsulinaemia</title><title>Diabetic medicine</title><addtitle>Diabet Med</addtitle><description>SUMMARY
Aims To compare the extent of hyperinsulinaemia among New Zealand Europeans and Polynesians (an ethnic group at high risk of Type 2 diabetes mellitus).
Methods A cross‐sectional survey from randomly selected households was conducted in inner urban South Auckland.
Subjects were either European, Maori or Pacific Islands Polynesians aged 40–79 years and were screened for diabetes using a random blood glucose. Those with an elevated result, and 20% randomly selected from those with a normal screening result, were invited to a 75‐g glucose tolerance test. WHO criteria (1998) for diabetes were used
Results In those aged 40–59 years, total prevalence of diabetes was 7.5 (6.2–9.0)% in Europeans but 21.1 (16.6–25.6)% among Maori and 25.0 (19.8–30.1)% among Pacific peoples; obesity (body mass index ≥ 31.0 kg/m2) was present in 26% Europeans, 63% Maori and 69% Pacific peoples. Non‐diabetic Polynesians were relatively hyperglycaemic and hyperinsulinaemic. After adjusting for the degree of obesity, Polynesians had similar insulin levels to Europeans.
Conclusions These findings indicate that Polynesians are not intrinsically insulin resistant as a group, a prerequisite found in most other ethnic groups at high risk of Type 2 diabetes mellitus. The high prevalence of Type 2 diabetes in Polynesians could be the result of their high prevalence of obesity.</description><subject>Adult</subject><subject>Aged</subject><subject>Australia - epidemiology</subject><subject>Biological and medical sciences</subject><subject>Blood Glucose - analysis</subject><subject>Diabetes Mellitus, Type 2 - epidemiology</subject><subject>Diabetes. Impaired glucose tolerance</subject><subject>Endocrine pancreas. Apud cells (diseases)</subject><subject>Endocrinopathies</subject><subject>Ethnic Groups</subject><subject>Etiopathogenesis. Screening. Investigations. Target tissue resistance</subject><subject>Europe - ethnology</subject><subject>European Continental Ancestry Group</subject><subject>Female</subject><subject>glucose</subject><subject>Humans</subject><subject>Hyperglycemia - epidemiology</subject><subject>Hyperinsulinism - epidemiology</subject><subject>insulin</subject><subject>Insulin - blood</subject><subject>Insulin Resistance</subject><subject>Male</subject><subject>Mass Screening</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>New Zealand - epidemiology</subject><subject>obesity</subject><subject>Obesity - epidemiology</subject><subject>Polynesia - ethnology</subject><subject>Polynesian</subject><subject>Type 2 diabetes mellitus</subject><subject>Urban Population - statistics & numerical data</subject><issn>0742-3071</issn><issn>1464-5491</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkEFv0zAYhq1paCuDvzBZQtot4XPs2AnaZWyjIG2wQxG7WXbyVbgkThcnovn3OLQqV0627Of19_ohhDJIGQj5fpMyIUWSi5KlGQBLAQTP090JWRwvTskClMgSDoqdk9chbCKYlbw8I-eMcVYUvFyQ1VPXTB6DMz58oNu-80iHjnY2Hg0TNb6mq2mLNKO1MxYHDLTFpnHDGKgdB-q7gf6MQO98GBvnDbbOvCGv1qYJ-PawXpDvn-5Xt5-Th2_LL7c3D0klCsgTNFihUhytwZxxKaWoc7S45tKWwEDVmairynBWSi7AZPE7ueHWouUSJOcX5Gr_buz9MmIYdOtCFesZj90YtIICRAZ5BIs9WPVdCD2u9bZ3reknzUDPRvVGz-L0LE7PRvVfo3oXo5eHGaNtsf4XPCiMwLsDYEJlmnVvfOXCkStVJsq56vWe-u0anP57vL57vI-bGE_2cRcG3B3jpv-lpeIq1z--LrV4fLr7qJbPmvM_p3igSA</recordid><startdate>200103</startdate><enddate>200103</enddate><creator>Simmons, D.</creator><creator>Thompson, C. F.</creator><creator>Volklander, D.</creator><general>Blackwell Science Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200103</creationdate><title>Polynesians: prone to obesity and Type 2 diabetes mellitus but not hyperinsulinaemia</title><author>Simmons, D. ; Thompson, C. F. ; Volklander, D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4805-eaece773ebae5136664d5ebef36b90107d24dcca3196340a27425a3bbeb360633</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Australia - epidemiology</topic><topic>Biological and medical sciences</topic><topic>Blood Glucose - analysis</topic><topic>Diabetes Mellitus, Type 2 - epidemiology</topic><topic>Diabetes. Impaired glucose tolerance</topic><topic>Endocrine pancreas. Apud cells (diseases)</topic><topic>Endocrinopathies</topic><topic>Ethnic Groups</topic><topic>Etiopathogenesis. Screening. Investigations. Target tissue resistance</topic><topic>Europe - ethnology</topic><topic>European Continental Ancestry Group</topic><topic>Female</topic><topic>glucose</topic><topic>Humans</topic><topic>Hyperglycemia - epidemiology</topic><topic>Hyperinsulinism - epidemiology</topic><topic>insulin</topic><topic>Insulin - blood</topic><topic>Insulin Resistance</topic><topic>Male</topic><topic>Mass Screening</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>New Zealand - epidemiology</topic><topic>obesity</topic><topic>Obesity - epidemiology</topic><topic>Polynesia - ethnology</topic><topic>Polynesian</topic><topic>Type 2 diabetes mellitus</topic><topic>Urban Population - statistics & numerical data</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Simmons, D.</creatorcontrib><creatorcontrib>Thompson, C. F.</creatorcontrib><creatorcontrib>Volklander, D.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Diabetic medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Simmons, D.</au><au>Thompson, C. F.</au><au>Volklander, D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Polynesians: prone to obesity and Type 2 diabetes mellitus but not hyperinsulinaemia</atitle><jtitle>Diabetic medicine</jtitle><addtitle>Diabet Med</addtitle><date>2001-03</date><risdate>2001</risdate><volume>18</volume><issue>3</issue><spage>193</spage><epage>198</epage><pages>193-198</pages><issn>0742-3071</issn><eissn>1464-5491</eissn><coden>DIMEEV</coden><abstract>SUMMARY
Aims To compare the extent of hyperinsulinaemia among New Zealand Europeans and Polynesians (an ethnic group at high risk of Type 2 diabetes mellitus).
Methods A cross‐sectional survey from randomly selected households was conducted in inner urban South Auckland.
Subjects were either European, Maori or Pacific Islands Polynesians aged 40–79 years and were screened for diabetes using a random blood glucose. Those with an elevated result, and 20% randomly selected from those with a normal screening result, were invited to a 75‐g glucose tolerance test. WHO criteria (1998) for diabetes were used
Results In those aged 40–59 years, total prevalence of diabetes was 7.5 (6.2–9.0)% in Europeans but 21.1 (16.6–25.6)% among Maori and 25.0 (19.8–30.1)% among Pacific peoples; obesity (body mass index ≥ 31.0 kg/m2) was present in 26% Europeans, 63% Maori and 69% Pacific peoples. Non‐diabetic Polynesians were relatively hyperglycaemic and hyperinsulinaemic. After adjusting for the degree of obesity, Polynesians had similar insulin levels to Europeans.
Conclusions These findings indicate that Polynesians are not intrinsically insulin resistant as a group, a prerequisite found in most other ethnic groups at high risk of Type 2 diabetes mellitus. The high prevalence of Type 2 diabetes in Polynesians could be the result of their high prevalence of obesity.</abstract><cop>Oxford, UK</cop><pub>Blackwell Science Ltd</pub><pmid>11318839</pmid><doi>10.1046/j.1464-5491.2001.00435.x</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Aged Australia - epidemiology Biological and medical sciences Blood Glucose - analysis Diabetes Mellitus, Type 2 - epidemiology Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Ethnic Groups Etiopathogenesis. Screening. Investigations. Target tissue resistance Europe - ethnology European Continental Ancestry Group Female glucose Humans Hyperglycemia - epidemiology Hyperinsulinism - epidemiology insulin Insulin - blood Insulin Resistance Male Mass Screening Medical sciences Middle Aged New Zealand - epidemiology obesity Obesity - epidemiology Polynesia - ethnology Polynesian Type 2 diabetes mellitus Urban Population - statistics & numerical data |
| title | Polynesians: prone to obesity and Type 2 diabetes mellitus but not hyperinsulinaemia |
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