Effects of Prostaglandin E1, Dobutamine and Placebo on Hemodynamic, Renal and Neurohumoral Variables in Patients with Advanced Heart Failure

Excessive neurohumoral activity remains a major burden to the circulation of patients with advanced heart failure. Prostaglandin El (PGE1), a balanced i.v. vasodilator, was shown to elicit favorable hemodynamic and clinical effects in this cohort. A prospective randomized parallel group trial was pe...

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Veröffentlicht in:	Japanese Heart Journal 1999, Vol.40(3), pp.321-334
Hauptverfasser:	WIMMER, Andreas, STANEK, Brigitte, KUBECOVA, Lea, VITOVEC, Jiri, SPINAR, Jindrich, YILMAZ, Nilgryn, KOS, Thomas, HARTTER, Engelbert, FREY, Bernhard, PACHER, Richard
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced heart failure Alprostadil - therapeutic use Atrial Natriuretic Factor - blood Biological and medical sciences Blood Pressure - drug effects Cardiology. Vascular system Cardiotonic Agents - therapeutic use Dobutamine Dobutamine - therapeutic use Endothelins - blood Female Glomerular filtration rate Glomerular Filtration Rate - drug effects Heart Heart Failure - blood Heart Failure - drug therapy Heart Failure - physiopathology Heart failure, cardiogenic pulmonary edema, cardiac enlargement Heart Rate - drug effects Hemodynamics Hemodynamics - drug effects Humans Male Medical sciences Middle Aged Norepinephrine - blood Prospective Studies Prostaglandin E1 Renal Circulation - drug effects Renal plasma flow Vasodilator Agents - therapeutic use
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