BCG infection in allergen-presensitized rats suppresses Th2 immune response and prevents the development of allergic asthmatic reaction

Recent investigations demonstrate that bacille Calmette-Guerin (BCG), a potent inducer of Th1 response, infection prior to allergen sensitization inhibits Th2 immune responses to the allergen. However, it is not clear whether BCG infection in allergen-presensitized rats switches off Th2 response and...

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Veröffentlicht in:	Journal of clinical immunology 2001, Vol.21 (1), p.51-59
Hauptverfasser:	KOH, Youngil I, CHOI, Inseon S, KIM, Won-Young
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergens - immunology Animals Asthma - prevention & control BCG Vaccine - immunology Biological and medical sciences Eosinophilia - etiology Immunopathology Immunotherapy (general aspects) Interferon-gamma - biosynthesis Interleukin-4 - biosynthesis Male Medical sciences Mycobacterium bovis ovalbumin Ovalbumin - immunology Rats Rats, Sprague-Dawley Th2 Cells - immunology Vaccination
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