Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women: The KANWU study

The amount and quality of fat in the diet could be of importance for development of insulin resistance and related metabolic disorders. Our aim was to determine whether a change in dietary fat quality alone could alter insulin action in humans. The KANWU study included 162 healthy subjects chosen at...

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Veröffentlicht in:	Diabetologia 2001-03, Vol.44 (3), p.312-319
Hauptverfasser:	VESSBY, B, UUSITUPA, M, CALVERT, G. D, MAFFETONE, A, PEDERSEN, E, GUSTAFSSON, I.-B, STORLIEN, L. H, HERMANSEN, K, RICCARDI, G, RIVELLESE, A. A, TAPSELL, L. C, NÄLSEN, C, BERGLUND, L, LOUHERANTA, A, RASMUSSEN, B. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Apolipoprotein A-I - blood Apolipoproteins B - blood Biological and medical sciences Blood Glucose - drug effects Blood Glucose - metabolism Cholesterol - blood Cholesterol, HDL - blood Cholesterol, LDL - blood Diabetes. Impaired glucose tolerance Dietary Fats - pharmacology Dietary Fats, Unsaturated - pharmacology Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Fatty Acids, Monounsaturated - pharmacology Fatty Acids, Omega-3 - pharmacology Female Fish Oils - pharmacology Glucose Tolerance Test Humans Insulin - blood Insulin - metabolism Insulin Secretion Lipoprotein(a) - blood Male Medical sciences Middle Aged Phospholipids - blood Phospholipids - chemistry Reference Values Triglycerides - blood
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