Aortic valve replacement: is the stentless xenograft an alternative to the homograft? midterm results
Background. This study was performed to assess the midterm clinical results after aortic valve replacement (AVR) with stentless xenograft (SX) compared with cryopreserved aortic or pulmonary homografts (HX). Methods. In 139 patients (< 60 years) undergoing elective AVR, 59 HX and 80 SX were inser...
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| Veröffentlicht in: | The Annals of thoracic surgery 1999-09, Vol.68 (3), p.919-924 |
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| creator | Gross, Christoph Harringer, Wolfgang Beran, Helmut Mair, Rudolf Sihorsch, Kurt Hofmann, Robert Brücke, Peter |
| description | Background. This study was performed to assess the midterm clinical results after aortic valve replacement (AVR) with stentless xenograft (SX) compared with cryopreserved aortic or pulmonary homografts (HX).
Methods. In 139 patients (< 60 years) undergoing elective AVR, 59 HX and 80 SX were inserted. All patients were followed clinically and by color flow Doppler echocardiography for 45 ± 12 months (range 31–58 months).
Results. There were 5 in-hospital deaths (3.5%): 4 HX and 1 SX (
p = NS). The mean gradient was 6 ± 2 mm Hg in HX versus 13 ± 6 mm Hg in SX (
p < 0.001) and remained unchanged during follow-up. Actuarial survival (HX 77%, SX 80%), freedom from endocarditis (HX 91%, SX 99%), freedom from thromboembolic events (HX 98%, SX 90%), and freedom from reoperation (HX 98%, SX 100%) were comparable between groups after 58 months.
Conclusions. Despite slightly higher transvalvular gradients, the stentless aortic valve achieved excellent midterm results, when compared with homografts. |
| doi_str_mv | 10.1016/S0003-4975(99)00535-4 |
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Methods. In 139 patients (< 60 years) undergoing elective AVR, 59 HX and 80 SX were inserted. All patients were followed clinically and by color flow Doppler echocardiography for 45 ± 12 months (range 31–58 months).
Results. There were 5 in-hospital deaths (3.5%): 4 HX and 1 SX (
p = NS). The mean gradient was 6 ± 2 mm Hg in HX versus 13 ± 6 mm Hg in SX (
p < 0.001) and remained unchanged during follow-up. Actuarial survival (HX 77%, SX 80%), freedom from endocarditis (HX 91%, SX 99%), freedom from thromboembolic events (HX 98%, SX 90%), and freedom from reoperation (HX 98%, SX 100%) were comparable between groups after 58 months.
Conclusions. Despite slightly higher transvalvular gradients, the stentless aortic valve achieved excellent midterm results, when compared with homografts.</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/S0003-4975(99)00535-4</identifier><identifier>PMID: 10509984</identifier><identifier>CODEN: ATHSAK</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Actuarial Analysis ; Aged ; Aortic Valve - surgery ; Aortic Valve - transplantation ; Biological and medical sciences ; Bioprosthesis - adverse effects ; Echocardiography, Doppler, Color ; Endocarditis - etiology ; Female ; Heart Valve Prosthesis - adverse effects ; Heart Valve Prosthesis Implantation - adverse effects ; Heart Valve Prosthesis Implantation - mortality ; Hospital Mortality ; Humans ; Male ; Medical sciences ; Prospective Studies ; Prosthesis Design ; Pulmonary Valve - transplantation ; Reoperation ; Stents ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the heart ; Survival Rate ; Thromboembolism - etiology ; Transplantation, Homologous</subject><ispartof>The Annals of thoracic surgery, 1999-09, Vol.68 (3), p.919-924</ispartof><rights>1999 The Society of Thoracic Surgeons</rights><rights>1999 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c472t-649da481b6e31389158f5eab864dec05b6ddb0eb21b7b85b665d5c5129ab6e3</citedby><cites>FETCH-LOGICAL-c472t-649da481b6e31389158f5eab864dec05b6ddb0eb21b7b85b665d5c5129ab6e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0003497599005354$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1953138$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10509984$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gross, Christoph</creatorcontrib><creatorcontrib>Harringer, Wolfgang</creatorcontrib><creatorcontrib>Beran, Helmut</creatorcontrib><creatorcontrib>Mair, Rudolf</creatorcontrib><creatorcontrib>Sihorsch, Kurt</creatorcontrib><creatorcontrib>Hofmann, Robert</creatorcontrib><creatorcontrib>Brücke, Peter</creatorcontrib><title>Aortic valve replacement: is the stentless xenograft an alternative to the homograft? midterm results</title><title>The Annals of thoracic surgery</title><addtitle>Ann Thorac Surg</addtitle><description>Background. This study was performed to assess the midterm clinical results after aortic valve replacement (AVR) with stentless xenograft (SX) compared with cryopreserved aortic or pulmonary homografts (HX).
Methods. In 139 patients (< 60 years) undergoing elective AVR, 59 HX and 80 SX were inserted. All patients were followed clinically and by color flow Doppler echocardiography for 45 ± 12 months (range 31–58 months).
Results. There were 5 in-hospital deaths (3.5%): 4 HX and 1 SX (
p = NS). The mean gradient was 6 ± 2 mm Hg in HX versus 13 ± 6 mm Hg in SX (
p < 0.001) and remained unchanged during follow-up. Actuarial survival (HX 77%, SX 80%), freedom from endocarditis (HX 91%, SX 99%), freedom from thromboembolic events (HX 98%, SX 90%), and freedom from reoperation (HX 98%, SX 100%) were comparable between groups after 58 months.
Conclusions. Despite slightly higher transvalvular gradients, the stentless aortic valve achieved excellent midterm results, when compared with homografts.</description><subject>Actuarial Analysis</subject><subject>Aged</subject><subject>Aortic Valve - surgery</subject><subject>Aortic Valve - transplantation</subject><subject>Biological and medical sciences</subject><subject>Bioprosthesis - adverse effects</subject><subject>Echocardiography, Doppler, Color</subject><subject>Endocarditis - etiology</subject><subject>Female</subject><subject>Heart Valve Prosthesis - adverse effects</subject><subject>Heart Valve Prosthesis Implantation - adverse effects</subject><subject>Heart Valve Prosthesis Implantation - mortality</subject><subject>Hospital Mortality</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Prospective Studies</subject><subject>Prosthesis Design</subject><subject>Pulmonary Valve - transplantation</subject><subject>Reoperation</subject><subject>Stents</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the heart</subject><subject>Survival Rate</subject><subject>Thromboembolism - etiology</subject><subject>Transplantation, Homologous</subject><issn>0003-4975</issn><issn>1552-6259</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEFP2zAYhq2JaRS2n7DJBzTBIcxO7STmgqoK2KRKHNjdcuwvw8hJij-32v49blMxbpysV9_zfrYfQr5ydskZr348MMbmhVC1PFfqgjE5l4X4QGZcyrKoSqmOyOwVOSYniE85lnn8iRxzJplSjZgRWIwxeUu3JmyBRlgHY6GHIV1RjzQ9AsWUUwBE-heG8U80XaJmoCYkiINJPtfSuCcfx36aX9Peuzzu80LchISfycfOBIQvh_OUPNze_F7-LFb3d7-Wi1VhRV2mohLKGdHwtoI5nzeKy6aTYNqmEg4sk23lXMugLXlbt02OlXTSSl4qs6ucku_T1nUcnzeASfceLYRgBhg3qGtWK9HUTQblBNo4Ikbo9Dr63sR_mjO9s6v3dvVOnVZK7-1qkXvfDhds2h7cm9akMwNnB8CgNaGLZrAe_3NK7v6VsesJg-xi6yFqtB4GC85HsEm70b_zkhcyxpg7</recordid><startdate>19990901</startdate><enddate>19990901</enddate><creator>Gross, Christoph</creator><creator>Harringer, Wolfgang</creator><creator>Beran, Helmut</creator><creator>Mair, Rudolf</creator><creator>Sihorsch, Kurt</creator><creator>Hofmann, Robert</creator><creator>Brücke, Peter</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19990901</creationdate><title>Aortic valve replacement: is the stentless xenograft an alternative to the homograft? midterm results</title><author>Gross, Christoph ; Harringer, Wolfgang ; Beran, Helmut ; Mair, Rudolf ; Sihorsch, Kurt ; Hofmann, Robert ; Brücke, Peter</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c472t-649da481b6e31389158f5eab864dec05b6ddb0eb21b7b85b665d5c5129ab6e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Actuarial Analysis</topic><topic>Aged</topic><topic>Aortic Valve - surgery</topic><topic>Aortic Valve - transplantation</topic><topic>Biological and medical sciences</topic><topic>Bioprosthesis - adverse effects</topic><topic>Echocardiography, Doppler, Color</topic><topic>Endocarditis - etiology</topic><topic>Female</topic><topic>Heart Valve Prosthesis - adverse effects</topic><topic>Heart Valve Prosthesis Implantation - adverse effects</topic><topic>Heart Valve Prosthesis Implantation - mortality</topic><topic>Hospital Mortality</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Prospective Studies</topic><topic>Prosthesis Design</topic><topic>Pulmonary Valve - transplantation</topic><topic>Reoperation</topic><topic>Stents</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the heart</topic><topic>Survival Rate</topic><topic>Thromboembolism - etiology</topic><topic>Transplantation, Homologous</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gross, Christoph</creatorcontrib><creatorcontrib>Harringer, Wolfgang</creatorcontrib><creatorcontrib>Beran, Helmut</creatorcontrib><creatorcontrib>Mair, Rudolf</creatorcontrib><creatorcontrib>Sihorsch, Kurt</creatorcontrib><creatorcontrib>Hofmann, Robert</creatorcontrib><creatorcontrib>Brücke, Peter</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gross, Christoph</au><au>Harringer, Wolfgang</au><au>Beran, Helmut</au><au>Mair, Rudolf</au><au>Sihorsch, Kurt</au><au>Hofmann, Robert</au><au>Brücke, Peter</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Aortic valve replacement: is the stentless xenograft an alternative to the homograft? midterm results</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>1999-09-01</date><risdate>1999</risdate><volume>68</volume><issue>3</issue><spage>919</spage><epage>924</epage><pages>919-924</pages><issn>0003-4975</issn><eissn>1552-6259</eissn><coden>ATHSAK</coden><abstract>Background. This study was performed to assess the midterm clinical results after aortic valve replacement (AVR) with stentless xenograft (SX) compared with cryopreserved aortic or pulmonary homografts (HX).
Methods. In 139 patients (< 60 years) undergoing elective AVR, 59 HX and 80 SX were inserted. All patients were followed clinically and by color flow Doppler echocardiography for 45 ± 12 months (range 31–58 months).
Results. There were 5 in-hospital deaths (3.5%): 4 HX and 1 SX (
p = NS). The mean gradient was 6 ± 2 mm Hg in HX versus 13 ± 6 mm Hg in SX (
p < 0.001) and remained unchanged during follow-up. Actuarial survival (HX 77%, SX 80%), freedom from endocarditis (HX 91%, SX 99%), freedom from thromboembolic events (HX 98%, SX 90%), and freedom from reoperation (HX 98%, SX 100%) were comparable between groups after 58 months.
Conclusions. Despite slightly higher transvalvular gradients, the stentless aortic valve achieved excellent midterm results, when compared with homografts.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>10509984</pmid><doi>10.1016/S0003-4975(99)00535-4</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Actuarial Analysis Aged Aortic Valve - surgery Aortic Valve - transplantation Biological and medical sciences Bioprosthesis - adverse effects Echocardiography, Doppler, Color Endocarditis - etiology Female Heart Valve Prosthesis - adverse effects Heart Valve Prosthesis Implantation - adverse effects Heart Valve Prosthesis Implantation - mortality Hospital Mortality Humans Male Medical sciences Prospective Studies Prosthesis Design Pulmonary Valve - transplantation Reoperation Stents Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart Survival Rate Thromboembolism - etiology Transplantation, Homologous |
| title | Aortic valve replacement: is the stentless xenograft an alternative to the homograft? midterm results |
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