An analysis of risk factors for upper urinary tract deterioration in patients with myelodysplasia
Objective To identify the risk factors for upper urinary tract deterioration in a retrospective study of patients with myelodysplasia. Patients and methods The medical history, radiographic studies and urodynamic results from 39 children with myelodysplasia who were treated at our hospital were re...
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| Veröffentlicht in: | BJU international 1999-10, Vol.84 (6), p.679-682 |
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| creator | SEKI, N AKAZAWA, K SENOH, K KUBO, S TSUNODA, T KIMOTO, Y NAITO, S |
| description | Objective
To identify the risk factors for upper urinary tract deterioration in a retrospective study of patients with myelodysplasia.
Patients and methods
The medical history, radiographic studies and urodynamic results from 39 children with myelodysplasia who were treated at our hospital were reviewed retrospectively to obtain more accurate data in the prognosis of such patients. The upper urinary tracts were assessed by cysto‐urethrography and excretory urography to determine the incidence of vesico‐ureteric reflux (VUR) and hydronephrosis. The relationships between the urodynamic variables, including vesical compliance, detrusor hyper‐reflexia, detrusor‐sphincter dyssynergia (DSD) and the maximum urethral closing pressure (MUCP) to such upper tract deterioration were evaluated using both univariate and multiple logistic regression analysis.
Results
The univariate analysis showed low vesical compliance, a high level of MUCP and the presence of DSD to be significant factors for the incidence of VUR. Low vesical compliance and a high level of MUCP also correlated with the incidence of hydronephrosis. The multivariate analysis showed a significant relationship between urodynamic values and upper urinary tract deterioration. The incidence of VUR was strongly correlated with a high MUCP and the presence of DSD. A high MUCP was also a significant factor in the incidence of hydronephrosis.
Conclusion
Urodynamic results associated directly with the abnormal function of urethral control are significantly correlated with the cause of upper tract deterioration in patients with myelodysplasia. |
| doi_str_mv | 10.1046/j.1464-410x.1999.00220.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_70794578</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>70794578</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4430-8d4c1819e61286269aa1a2c60131867ae67cd13f6c65a1ea34dd77e8ab856dbe3</originalsourceid><addsrcrecordid>eNqNkE1v1DAQhi0Eoh_wF5APFbdNPYnjJFIvpQJaVIkLlbhZs85EeJuNgyerbv49DrutOHKxX3me8diPEBJUBkqby00G2uiVBrXPoGmaTKk8V9n-lTh9Lvx8_ZxVY07EGfNGqXRgyrfiBFQJCqA8FXg9SBywn9mzDJ2Mnh9lh24KkWUXotyNI6U1-gHjLKeYSrKliaIPEScfBukHOaZEw8TyyU-_5HamPrQzjz2yx3fiTYc90_vjfi4evnz-cXO7uv_-9e7m-n7ltC7Uqm61gxoaMpDXJjcNImDujIICalMhmcq1UHTGmRKBsNBtW1VU47ouTbum4lx8PNw7xvB7RzzZrWdHfY8DhR3bSlWNLqs6gfUBdDEwR-rsGP02_c6Csoteu7GLObvotYte-1ev3afWD8cZu_WW2n8aDz4TcHEEkB32XcTBeX7hcqVMkS9PuDpgT76n-b_n20_fHlIo_gDYxJeh</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>70794578</pqid></control><display><type>article</type><title>An analysis of risk factors for upper urinary tract deterioration in patients with myelodysplasia</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>SEKI, N ; AKAZAWA, K ; SENOH, K ; KUBO, S ; TSUNODA, T ; KIMOTO, Y ; NAITO, S</creator><creatorcontrib>SEKI, N ; AKAZAWA, K ; SENOH, K ; KUBO, S ; TSUNODA, T ; KIMOTO, Y ; NAITO, S</creatorcontrib><description>Objective
To identify the risk factors for upper urinary tract deterioration in a retrospective study of patients with myelodysplasia.
Patients and methods
The medical history, radiographic studies and urodynamic results from 39 children with myelodysplasia who were treated at our hospital were reviewed retrospectively to obtain more accurate data in the prognosis of such patients. The upper urinary tracts were assessed by cysto‐urethrography and excretory urography to determine the incidence of vesico‐ureteric reflux (VUR) and hydronephrosis. The relationships between the urodynamic variables, including vesical compliance, detrusor hyper‐reflexia, detrusor‐sphincter dyssynergia (DSD) and the maximum urethral closing pressure (MUCP) to such upper tract deterioration were evaluated using both univariate and multiple logistic regression analysis.
Results
The univariate analysis showed low vesical compliance, a high level of MUCP and the presence of DSD to be significant factors for the incidence of VUR. Low vesical compliance and a high level of MUCP also correlated with the incidence of hydronephrosis. The multivariate analysis showed a significant relationship between urodynamic values and upper urinary tract deterioration. The incidence of VUR was strongly correlated with a high MUCP and the presence of DSD. A high MUCP was also a significant factor in the incidence of hydronephrosis.
Conclusion
Urodynamic results associated directly with the abnormal function of urethral control are significantly correlated with the cause of upper tract deterioration in patients with myelodysplasia.</description><identifier>ISSN: 1464-4096</identifier><identifier>EISSN: 1464-410X</identifier><identifier>DOI: 10.1046/j.1464-410x.1999.00220.x</identifier><identifier>PMID: 10510115</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Science Ltd</publisher><subject>Adolescent ; Biological and medical sciences ; Child ; Child, Preschool ; detrusor‐sphincter dyssynergia ; Female ; Humans ; Hydronephrosis - complications ; Hydronephrosis - diagnosis ; Infant ; Infant, Newborn ; Male ; Medical sciences ; Myelodysplasia ; Nephrology. Urinary tract diseases ; Neural Tube Defects - complications ; Prognosis ; Retrospective Studies ; Risk Factors ; Urinary system involvement in other diseases. Miscellaneous ; Urinary tract. Prostate gland ; Vesico-Ureteral Reflux - complications ; Vesico-Ureteral Reflux - diagnosis ; vesico‐ureteric reflux</subject><ispartof>BJU international, 1999-10, Vol.84 (6), p.679-682</ispartof><rights>1999 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4430-8d4c1819e61286269aa1a2c60131867ae67cd13f6c65a1ea34dd77e8ab856dbe3</citedby><cites>FETCH-LOGICAL-c4430-8d4c1819e61286269aa1a2c60131867ae67cd13f6c65a1ea34dd77e8ab856dbe3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1046%2Fj.1464-410x.1999.00220.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1046%2Fj.1464-410x.1999.00220.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2006328$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10510115$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SEKI, N</creatorcontrib><creatorcontrib>AKAZAWA, K</creatorcontrib><creatorcontrib>SENOH, K</creatorcontrib><creatorcontrib>KUBO, S</creatorcontrib><creatorcontrib>TSUNODA, T</creatorcontrib><creatorcontrib>KIMOTO, Y</creatorcontrib><creatorcontrib>NAITO, S</creatorcontrib><title>An analysis of risk factors for upper urinary tract deterioration in patients with myelodysplasia</title><title>BJU international</title><addtitle>BJU Int</addtitle><description>Objective
To identify the risk factors for upper urinary tract deterioration in a retrospective study of patients with myelodysplasia.
Patients and methods
The medical history, radiographic studies and urodynamic results from 39 children with myelodysplasia who were treated at our hospital were reviewed retrospectively to obtain more accurate data in the prognosis of such patients. The upper urinary tracts were assessed by cysto‐urethrography and excretory urography to determine the incidence of vesico‐ureteric reflux (VUR) and hydronephrosis. The relationships between the urodynamic variables, including vesical compliance, detrusor hyper‐reflexia, detrusor‐sphincter dyssynergia (DSD) and the maximum urethral closing pressure (MUCP) to such upper tract deterioration were evaluated using both univariate and multiple logistic regression analysis.
Results
The univariate analysis showed low vesical compliance, a high level of MUCP and the presence of DSD to be significant factors for the incidence of VUR. Low vesical compliance and a high level of MUCP also correlated with the incidence of hydronephrosis. The multivariate analysis showed a significant relationship between urodynamic values and upper urinary tract deterioration. The incidence of VUR was strongly correlated with a high MUCP and the presence of DSD. A high MUCP was also a significant factor in the incidence of hydronephrosis.
Conclusion
Urodynamic results associated directly with the abnormal function of urethral control are significantly correlated with the cause of upper tract deterioration in patients with myelodysplasia.</description><subject>Adolescent</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>detrusor‐sphincter dyssynergia</subject><subject>Female</subject><subject>Humans</subject><subject>Hydronephrosis - complications</subject><subject>Hydronephrosis - diagnosis</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Myelodysplasia</subject><subject>Nephrology. Urinary tract diseases</subject><subject>Neural Tube Defects - complications</subject><subject>Prognosis</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Urinary system involvement in other diseases. Miscellaneous</subject><subject>Urinary tract. Prostate gland</subject><subject>Vesico-Ureteral Reflux - complications</subject><subject>Vesico-Ureteral Reflux - diagnosis</subject><subject>vesico‐ureteric reflux</subject><issn>1464-4096</issn><issn>1464-410X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkE1v1DAQhi0Eoh_wF5APFbdNPYnjJFIvpQJaVIkLlbhZs85EeJuNgyerbv49DrutOHKxX3me8diPEBJUBkqby00G2uiVBrXPoGmaTKk8V9n-lTh9Lvx8_ZxVY07EGfNGqXRgyrfiBFQJCqA8FXg9SBywn9mzDJ2Mnh9lh24KkWUXotyNI6U1-gHjLKeYSrKliaIPEScfBukHOaZEw8TyyU-_5HamPrQzjz2yx3fiTYc90_vjfi4evnz-cXO7uv_-9e7m-n7ltC7Uqm61gxoaMpDXJjcNImDujIICalMhmcq1UHTGmRKBsNBtW1VU47ouTbum4lx8PNw7xvB7RzzZrWdHfY8DhR3bSlWNLqs6gfUBdDEwR-rsGP02_c6Csoteu7GLObvotYte-1ev3afWD8cZu_WW2n8aDz4TcHEEkB32XcTBeX7hcqVMkS9PuDpgT76n-b_n20_fHlIo_gDYxJeh</recordid><startdate>199910</startdate><enddate>199910</enddate><creator>SEKI, N</creator><creator>AKAZAWA, K</creator><creator>SENOH, K</creator><creator>KUBO, S</creator><creator>TSUNODA, T</creator><creator>KIMOTO, Y</creator><creator>NAITO, S</creator><general>Blackwell Science Ltd</general><general>Blackwell</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199910</creationdate><title>An analysis of risk factors for upper urinary tract deterioration in patients with myelodysplasia</title><author>SEKI, N ; AKAZAWA, K ; SENOH, K ; KUBO, S ; TSUNODA, T ; KIMOTO, Y ; NAITO, S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4430-8d4c1819e61286269aa1a2c60131867ae67cd13f6c65a1ea34dd77e8ab856dbe3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Adolescent</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>detrusor‐sphincter dyssynergia</topic><topic>Female</topic><topic>Humans</topic><topic>Hydronephrosis - complications</topic><topic>Hydronephrosis - diagnosis</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Myelodysplasia</topic><topic>Nephrology. Urinary tract diseases</topic><topic>Neural Tube Defects - complications</topic><topic>Prognosis</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Urinary system involvement in other diseases. Miscellaneous</topic><topic>Urinary tract. Prostate gland</topic><topic>Vesico-Ureteral Reflux - complications</topic><topic>Vesico-Ureteral Reflux - diagnosis</topic><topic>vesico‐ureteric reflux</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SEKI, N</creatorcontrib><creatorcontrib>AKAZAWA, K</creatorcontrib><creatorcontrib>SENOH, K</creatorcontrib><creatorcontrib>KUBO, S</creatorcontrib><creatorcontrib>TSUNODA, T</creatorcontrib><creatorcontrib>KIMOTO, Y</creatorcontrib><creatorcontrib>NAITO, S</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>BJU international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SEKI, N</au><au>AKAZAWA, K</au><au>SENOH, K</au><au>KUBO, S</au><au>TSUNODA, T</au><au>KIMOTO, Y</au><au>NAITO, S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An analysis of risk factors for upper urinary tract deterioration in patients with myelodysplasia</atitle><jtitle>BJU international</jtitle><addtitle>BJU Int</addtitle><date>1999-10</date><risdate>1999</risdate><volume>84</volume><issue>6</issue><spage>679</spage><epage>682</epage><pages>679-682</pages><issn>1464-4096</issn><eissn>1464-410X</eissn><abstract>Objective
To identify the risk factors for upper urinary tract deterioration in a retrospective study of patients with myelodysplasia.
Patients and methods
The medical history, radiographic studies and urodynamic results from 39 children with myelodysplasia who were treated at our hospital were reviewed retrospectively to obtain more accurate data in the prognosis of such patients. The upper urinary tracts were assessed by cysto‐urethrography and excretory urography to determine the incidence of vesico‐ureteric reflux (VUR) and hydronephrosis. The relationships between the urodynamic variables, including vesical compliance, detrusor hyper‐reflexia, detrusor‐sphincter dyssynergia (DSD) and the maximum urethral closing pressure (MUCP) to such upper tract deterioration were evaluated using both univariate and multiple logistic regression analysis.
Results
The univariate analysis showed low vesical compliance, a high level of MUCP and the presence of DSD to be significant factors for the incidence of VUR. Low vesical compliance and a high level of MUCP also correlated with the incidence of hydronephrosis. The multivariate analysis showed a significant relationship between urodynamic values and upper urinary tract deterioration. The incidence of VUR was strongly correlated with a high MUCP and the presence of DSD. A high MUCP was also a significant factor in the incidence of hydronephrosis.
Conclusion
Urodynamic results associated directly with the abnormal function of urethral control are significantly correlated with the cause of upper tract deterioration in patients with myelodysplasia.</abstract><cop>Oxford, UK</cop><pub>Blackwell Science Ltd</pub><pmid>10510115</pmid><doi>10.1046/j.1464-410x.1999.00220.x</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | BJU international, 1999-10, Vol.84 (6), p.679-682 |
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| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adolescent Biological and medical sciences Child Child, Preschool detrusor‐sphincter dyssynergia Female Humans Hydronephrosis - complications Hydronephrosis - diagnosis Infant Infant, Newborn Male Medical sciences Myelodysplasia Nephrology. Urinary tract diseases Neural Tube Defects - complications Prognosis Retrospective Studies Risk Factors Urinary system involvement in other diseases. Miscellaneous Urinary tract. Prostate gland Vesico-Ureteral Reflux - complications Vesico-Ureteral Reflux - diagnosis vesico‐ureteric reflux |
| title | An analysis of risk factors for upper urinary tract deterioration in patients with myelodysplasia |
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