ELISPOT Analysis of Hepatitis C Virus Protein-Specific IFN-γ-Producing Peripheral Blood Lymphocytes in Infected Humans with and without Cirrhosis

An improved ability to monitor hepatitis C virus (HCV)-specific T cell immunity in infected patients may provide novel information regarding the pathogenesis and prognosis of this infection. We used an ELISPOT assay to analyze a cross-section of HCV-infected humans. HCV-infected patients without cir...

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Veröffentlicht in:	Clinical immunology (Orlando, Fla.) Fla.), 2001-05, Vol.99 (2), p.232-240
Hauptverfasser:	Anthony, Donald D., Post, Anthony B., Valdez, Hernan, Peterson, Darrell L., Murphy, Madeleine, Heeger, Peter S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences cellular core protein cytokine Enzyme-Linked Immunosorbent Assay - methods g-Interferon Hepacivirus - immunology hepatitis C Hepatitis C Antigens hepatitis C virus Hepatitis C, Chronic - complications Hepatitis C, Chronic - etiology Hepatitis C, Chronic - immunology human Human viral diseases Humans immunity In Vitro Techniques Infectious diseases Interferon-gamma - biosynthesis Liver Cirrhosis - complications Liver Cirrhosis - etiology Liver Cirrhosis - immunology Medical sciences NS3 protein Prognosis T cell T-Lymphocytes - immunology Viral Core Proteins - immunology Viral diseases Viral hepatitis Viral Nonstructural Proteins - immunology
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