Peptide synthesis in organic media with subtilisin 72 immobilized on poly(vinyl alcohol)-cryogel carrier

Serine proteinase subtilisin 72 was covalently attached to the beads of poly(vinyl alcohol)-cryogel, a macroporous hydrogel prepared by the freeze–thaw technique. The immobilized enzyme was examined as a catalyst in the synthesis of protected peptides Z-Ala-Ala-Xaa-Phe-pNA (Xaa=Leu, Glu, Lys) in ace...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2001-04, Vol.11 (8), p.1005-1008
Hauptverfasser:	Bacheva, Anna V, Plieva, Fatima M, Lysogorskaya, Elena N, Filippova, Irina Yu, Lozinsky, Vladimir I
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetonitriles - chemistry Acetonitriles - pharmacology Bacillus subtilis - enzymology Catalysis Dimethylformamide - chemistry Dimethylformamide - pharmacology Enzymes, Immobilized - chemistry Enzymes, Immobilized - drug effects Enzymes, Immobilized - metabolism Hydrogel, Polyethylene Glycol Dimethacrylate - chemistry Peptide Biosynthesis Peptides - chemical synthesis Peptides - chemistry Peptides - metabolism Polyvinyl Alcohol - chemistry Serine Endopeptidases - drug effects Serine Endopeptidases - metabolism Subtilisins - drug effects Subtilisins - metabolism Time Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!