Treatments for spinal cord injury: Is there hope in neurosteroids?

In this review, we describe the current therapeutic strategies to find a cure for paralysis. We use the example of DHEA, a neurosteroid normally produced in the developing neural tube, to raise the hypothesis that such a class of molecules, capable of modulating proliferation of committed neural pre...

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Veröffentlicht in:	Journal of steroid biochemistry and molecular biology 2008-04, Vol.109 (3), p.307-313
1. Verfasser:	Compagnone, Nathalie A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Bladder control Cell Transplantation Clinical Trials as Topic DHEA Drug development Humans Medical sciences Methylprednisolone Motor recovery Myelin Sheath - drug effects Myelin Sheath - metabolism Nerve Regeneration Neuropharmacology Neuroprotective agent Neurosteroid Pharmacology. Drug treatments Sonic-hedgehog Spinal Cord Injuries - drug therapy Spinal Cord Injuries - pathology Spinal cord injury Steroids - therapeutic use
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