Can the time from synthesis design to validated chemistry be shortened?

The traditional way of identifying a potential new drug is to synthesize and test one candidate at a time. Design and optimization of reaction and workup conditions for each new molecule are accomplished through experimentation varying one‐variable‐at‐a‐time (OVAT). While this approach of drug disco...

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Veröffentlicht in:Medicinal research reviews 1999-09, Vol.19 (5), p.463-474
1. Verfasser: Pilipauskas, Daniel R.
Format: Artikel
Sprache:eng
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