Hookworm burden reductions in BALB/c mice vaccinated with recombinant Ancylostoma secreted proteins (ASPs) from Ancylostoma duodenale, Ancylostoma caninum and Necator americanus

Vaccination of mice with alum-precipitated recombinant Ancylostoma secreted protein-1 from the canine hookworm Ancylostoma caninum (Ac-ASP-1) results in protection against A. caninum larval challenge. Vaccine protection is manifested by host reductions in hookworm burden compared to control mice. Th...

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Veröffentlicht in:Vaccine 2000-01, Vol.18 (11), p.1096-1102
Hauptverfasser: Sen, Liu, Ghosh, Kashinath, Bin, Zhan, Qiang, Shan, Thompson, M.Greg, Hawdon, John M, Koski, Raymond A, Shuhua, Xiao, Hotez, Peter J
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Sprache:eng
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