Voltage-driven DNA translocations through a nanopore

We measure current blockade and time distributions for single-stranded DNA polymers during voltage-driven translocations through a single alpha-hemolysin pore. We use these data to determine the velocity of the polymers in the pore. Our measurements imply that, while polymers longer than the pore ar...

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Veröffentlicht in:	Physical review letters 2001-04, Vol.86 (15), p.3435-3438
Hauptverfasser:	Meller, A, Nivon, L, Branton, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Toxins - chemistry Bacterial Toxins - metabolism Diffusion DNA, Single-Stranded - chemistry DNA, Single-Stranded - metabolism Electrochemistry Electrostatics Hemolysin Proteins - chemistry Hemolysin Proteins - metabolism Lipid Bilayers - chemistry Lipid Bilayers - metabolism Membrane Potentials Membranes, Artificial Molecular dynamics Molecular structure Phosphatidylcholines - chemistry Phosphatidylcholines - metabolism Pore size Structure-Activity Relationship Thermal diffusion in solids
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