Primary Amebic Meningoencephalitis — Arizona, Florida, and Texas, 2007
Primary amebic meningoencephalitis (PAM) is a rare but nearly always fatal disease caused by infection with Naegleria fowleri, a thermophilic, free-living ameba found in freshwater environments. Infection results from water containing N. fowleri entering the nose, followed by migration of the amebae...
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creator | Matthews, S Ginzl, D Walsh, D Sherin, K Middaugh, J Hammond, R Bodager, D Komatsu, K Weiss, J Pascoe, N Marciano-Cabral, F Villegas, E Visvesvara, G Yoder, J Eddy, B Capewell, L Sriram, R Bandyopadhyay, K Qvarnstrom, Y DaSilva, A Johnston, S Xiao, L Hill, V Roy, S Beach, M.J |
description | Primary amebic meningoencephalitis (PAM) is a rare but nearly always fatal disease caused by infection with Naegleria fowleri, a thermophilic, free-living ameba found in freshwater environments. Infection results from water containing N. fowleri entering the nose, followed by migration of the amebae to the brain via the olfactory nerve. In 2007, six cases of PAM in the United States were reported to CDC; all six patients died. This report summarizes the investigations of the cases, which occurred in three southern tier states (Arizona, Florida, and Texas) during June-September and presents preliminary results from a review of PAM cases during 1937-2007. Because deaths from PAM often prompt heightened concern about the disease among the public, an updated and consistent approach to N. fowleri risk reduction messages, diagnosis and treatment, case reporting, and environmental sampling is needed. |
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Infection results from water containing N. fowleri entering the nose, followed by migration of the amebae to the brain via the olfactory nerve. In 2007, six cases of PAM in the United States were reported to CDC; all six patients died. This report summarizes the investigations of the cases, which occurred in three southern tier states (Arizona, Florida, and Texas) during June-September and presents preliminary results from a review of PAM cases during 1937-2007. Because deaths from PAM often prompt heightened concern about the disease among the public, an updated and consistent approach to N. fowleri risk reduction messages, diagnosis and treatment, case reporting, and environmental sampling is needed.</description><identifier>ISSN: 0149-2195</identifier><identifier>EISSN: 1545-861X</identifier><identifier>PMID: 18509301</identifier><language>eng</language><publisher>United States: Centers for Disease Control and Prevention</publisher><subject>Adolescent ; Amebiasis - diagnosis ; Amebiasis - epidemiology ; Amebiasis - therapy ; Animals ; Arizona - epidemiology ; Case studies ; Causes of ; Child ; Development and progression ; Disease outbreaks ; Epidemiology ; Fatal Outcome ; Florida - epidemiology ; Fresh water ; Fresh Water - parasitology ; Headache ; Hospital admissions ; Humans ; Infections ; Lakes ; Male ; Meningoencephalitis ; Meningoencephalitis - diagnosis ; Meningoencephalitis - epidemiology ; Meningoencephalitis - parasitology ; Meningoencephalitis - therapy ; Naegleria fowleri - isolation & purification ; Parasitic diseases ; Prevention ; River water ; Statistics ; Swimming ; Texas - epidemiology ; Water Microbiology</subject><ispartof>MMWR. 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Morbidity and mortality weekly report</title><addtitle>MMWR Morb Mortal Wkly Rep</addtitle><description>Primary amebic meningoencephalitis (PAM) is a rare but nearly always fatal disease caused by infection with Naegleria fowleri, a thermophilic, free-living ameba found in freshwater environments. Infection results from water containing N. fowleri entering the nose, followed by migration of the amebae to the brain via the olfactory nerve. In 2007, six cases of PAM in the United States were reported to CDC; all six patients died. This report summarizes the investigations of the cases, which occurred in three southern tier states (Arizona, Florida, and Texas) during June-September and presents preliminary results from a review of PAM cases during 1937-2007. Because deaths from PAM often prompt heightened concern about the disease among the public, an updated and consistent approach to N. fowleri risk reduction messages, diagnosis and treatment, case reporting, and environmental sampling is needed.</description><subject>Adolescent</subject><subject>Amebiasis - diagnosis</subject><subject>Amebiasis - epidemiology</subject><subject>Amebiasis - therapy</subject><subject>Animals</subject><subject>Arizona - epidemiology</subject><subject>Case studies</subject><subject>Causes of</subject><subject>Child</subject><subject>Development and progression</subject><subject>Disease outbreaks</subject><subject>Epidemiology</subject><subject>Fatal Outcome</subject><subject>Florida - epidemiology</subject><subject>Fresh water</subject><subject>Fresh Water - parasitology</subject><subject>Headache</subject><subject>Hospital admissions</subject><subject>Humans</subject><subject>Infections</subject><subject>Lakes</subject><subject>Male</subject><subject>Meningoencephalitis</subject><subject>Meningoencephalitis - diagnosis</subject><subject>Meningoencephalitis - epidemiology</subject><subject>Meningoencephalitis - parasitology</subject><subject>Meningoencephalitis - therapy</subject><subject>Naegleria fowleri - isolation & purification</subject><subject>Parasitic diseases</subject><subject>Prevention</subject><subject>River water</subject><subject>Statistics</subject><subject>Swimming</subject><subject>Texas - epidemiology</subject><subject>Water Microbiology</subject><issn>0149-2195</issn><issn>1545-861X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkcFOwzAMhisEYmPwCKCedlpR0jRteqwmxpCG4DAkblWaOl2mNBlNKwEnHoIn5Eko6kAgYR9s2d9vWfaBN8Y0ogGL8eOhN0Y4SoMQp3TknTi3RV9G0LE3woyilCA89pb3jap58-JnNRRK-LdglKksGAG7DdeqVc7_eHv3s0a9WsNn_kLbRpV9wk3pr-GZu5kfIpScekeSawdn-zjxHhZX6_kyWN1d38yzVVCFNGoDEUnAEcMkKiBGVBaJiCXwmBKUEMaKNKZUYMn7aoKwJKSQWLIwpZzSohQRmXjTYe6usU8duDavlROgNTdgO5cnKGEkRKwHgwGsuIZcGWnbhosKDDRcWwNS9eUMsyhO0xjhnr_8h--9hFqJfwXTX4INcN1unNVdq6xxf8GL_cpdUUOZ74aT599f6IHzAdi61jY__ZCQfghNyCfBKotM</recordid><startdate>20080530</startdate><enddate>20080530</enddate><creator>Matthews, S</creator><creator>Ginzl, D</creator><creator>Walsh, D</creator><creator>Sherin, K</creator><creator>Middaugh, J</creator><creator>Hammond, R</creator><creator>Bodager, D</creator><creator>Komatsu, K</creator><creator>Weiss, J</creator><creator>Pascoe, N</creator><creator>Marciano-Cabral, F</creator><creator>Villegas, E</creator><creator>Visvesvara, G</creator><creator>Yoder, J</creator><creator>Eddy, B</creator><creator>Capewell, L</creator><creator>Sriram, R</creator><creator>Bandyopadhyay, K</creator><creator>Qvarnstrom, Y</creator><creator>DaSilva, A</creator><creator>Johnston, S</creator><creator>Xiao, L</creator><creator>Hill, V</creator><creator>Roy, S</creator><creator>Beach, M.J</creator><general>Centers for Disease Control and Prevention</general><general>U.S. Government Printing Office</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20080530</creationdate><title>Primary Amebic Meningoencephalitis — Arizona, Florida, and Texas, 2007</title><author>Matthews, S ; Ginzl, D ; Walsh, D ; Sherin, K ; Middaugh, J ; Hammond, R ; Bodager, D ; Komatsu, K ; Weiss, J ; Pascoe, N ; Marciano-Cabral, F ; Villegas, E ; Visvesvara, G ; Yoder, J ; Eddy, B ; Capewell, L ; Sriram, R ; Bandyopadhyay, K ; Qvarnstrom, Y ; DaSilva, A ; Johnston, S ; Xiao, L ; Hill, V ; Roy, S ; Beach, M.J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g254t-c4fe148134be605fb7c6fea65307388b9655c1fac6f701f33bf1f8295a55bdc43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adolescent</topic><topic>Amebiasis - diagnosis</topic><topic>Amebiasis - epidemiology</topic><topic>Amebiasis - therapy</topic><topic>Animals</topic><topic>Arizona - epidemiology</topic><topic>Case studies</topic><topic>Causes of</topic><topic>Child</topic><topic>Development and progression</topic><topic>Disease outbreaks</topic><topic>Epidemiology</topic><topic>Fatal Outcome</topic><topic>Florida - epidemiology</topic><topic>Fresh water</topic><topic>Fresh Water - parasitology</topic><topic>Headache</topic><topic>Hospital admissions</topic><topic>Humans</topic><topic>Infections</topic><topic>Lakes</topic><topic>Male</topic><topic>Meningoencephalitis</topic><topic>Meningoencephalitis - diagnosis</topic><topic>Meningoencephalitis - epidemiology</topic><topic>Meningoencephalitis - parasitology</topic><topic>Meningoencephalitis - therapy</topic><topic>Naegleria fowleri - isolation & purification</topic><topic>Parasitic diseases</topic><topic>Prevention</topic><topic>River water</topic><topic>Statistics</topic><topic>Swimming</topic><topic>Texas - epidemiology</topic><topic>Water Microbiology</topic><toplevel>online_resources</toplevel><creatorcontrib>Matthews, S</creatorcontrib><creatorcontrib>Ginzl, D</creatorcontrib><creatorcontrib>Walsh, D</creatorcontrib><creatorcontrib>Sherin, K</creatorcontrib><creatorcontrib>Middaugh, J</creatorcontrib><creatorcontrib>Hammond, R</creatorcontrib><creatorcontrib>Bodager, D</creatorcontrib><creatorcontrib>Komatsu, K</creatorcontrib><creatorcontrib>Weiss, J</creatorcontrib><creatorcontrib>Pascoe, N</creatorcontrib><creatorcontrib>Marciano-Cabral, F</creatorcontrib><creatorcontrib>Villegas, E</creatorcontrib><creatorcontrib>Visvesvara, G</creatorcontrib><creatorcontrib>Yoder, J</creatorcontrib><creatorcontrib>Eddy, B</creatorcontrib><creatorcontrib>Capewell, L</creatorcontrib><creatorcontrib>Sriram, R</creatorcontrib><creatorcontrib>Bandyopadhyay, K</creatorcontrib><creatorcontrib>Qvarnstrom, Y</creatorcontrib><creatorcontrib>DaSilva, A</creatorcontrib><creatorcontrib>Johnston, S</creatorcontrib><creatorcontrib>Xiao, L</creatorcontrib><creatorcontrib>Hill, V</creatorcontrib><creatorcontrib>Roy, S</creatorcontrib><creatorcontrib>Beach, M.J</creatorcontrib><creatorcontrib>Centers for Disease Control and Prevention (CDC)</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>MMWR. 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Because deaths from PAM often prompt heightened concern about the disease among the public, an updated and consistent approach to N. fowleri risk reduction messages, diagnosis and treatment, case reporting, and environmental sampling is needed.</abstract><cop>United States</cop><pub>Centers for Disease Control and Prevention</pub><pmid>18509301</pmid><tpages>5</tpages></addata></record> |
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subjects | Adolescent Amebiasis - diagnosis Amebiasis - epidemiology Amebiasis - therapy Animals Arizona - epidemiology Case studies Causes of Child Development and progression Disease outbreaks Epidemiology Fatal Outcome Florida - epidemiology Fresh water Fresh Water - parasitology Headache Hospital admissions Humans Infections Lakes Male Meningoencephalitis Meningoencephalitis - diagnosis Meningoencephalitis - epidemiology Meningoencephalitis - parasitology Meningoencephalitis - therapy Naegleria fowleri - isolation & purification Parasitic diseases Prevention River water Statistics Swimming Texas - epidemiology Water Microbiology |
title | Primary Amebic Meningoencephalitis — Arizona, Florida, and Texas, 2007 |
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