Primary Amebic Meningoencephalitis — Arizona, Florida, and Texas, 2007

Primary amebic meningoencephalitis (PAM) is a rare but nearly always fatal disease caused by infection with Naegleria fowleri, a thermophilic, free-living ameba found in freshwater environments. Infection results from water containing N. fowleri entering the nose, followed by migration of the amebae...

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Veröffentlicht in:MMWR. Morbidity and mortality weekly report 2008-05, Vol.57 (21), p.573-577
Hauptverfasser: Matthews, S, Ginzl, D, Walsh, D, Sherin, K, Middaugh, J, Hammond, R, Bodager, D, Komatsu, K, Weiss, J, Pascoe, N, Marciano-Cabral, F, Villegas, E, Visvesvara, G, Yoder, J, Eddy, B, Capewell, L, Sriram, R, Bandyopadhyay, K, Qvarnstrom, Y, DaSilva, A, Johnston, S, Xiao, L, Hill, V, Roy, S, Beach, M.J
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container_issue 21
container_start_page 573
container_title MMWR. Morbidity and mortality weekly report
container_volume 57
creator Matthews, S
Ginzl, D
Walsh, D
Sherin, K
Middaugh, J
Hammond, R
Bodager, D
Komatsu, K
Weiss, J
Pascoe, N
Marciano-Cabral, F
Villegas, E
Visvesvara, G
Yoder, J
Eddy, B
Capewell, L
Sriram, R
Bandyopadhyay, K
Qvarnstrom, Y
DaSilva, A
Johnston, S
Xiao, L
Hill, V
Roy, S
Beach, M.J
description Primary amebic meningoencephalitis (PAM) is a rare but nearly always fatal disease caused by infection with Naegleria fowleri, a thermophilic, free-living ameba found in freshwater environments. Infection results from water containing N. fowleri entering the nose, followed by migration of the amebae to the brain via the olfactory nerve. In 2007, six cases of PAM in the United States were reported to CDC; all six patients died. This report summarizes the investigations of the cases, which occurred in three southern tier states (Arizona, Florida, and Texas) during June-September and presents preliminary results from a review of PAM cases during 1937-2007. Because deaths from PAM often prompt heightened concern about the disease among the public, an updated and consistent approach to N. fowleri risk reduction messages, diagnosis and treatment, case reporting, and environmental sampling is needed.
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subjects Adolescent
Amebiasis - diagnosis
Amebiasis - epidemiology
Amebiasis - therapy
Animals
Arizona - epidemiology
Case studies
Causes of
Child
Development and progression
Disease outbreaks
Epidemiology
Fatal Outcome
Florida - epidemiology
Fresh water
Fresh Water - parasitology
Headache
Hospital admissions
Humans
Infections
Lakes
Male
Meningoencephalitis
Meningoencephalitis - diagnosis
Meningoencephalitis - epidemiology
Meningoencephalitis - parasitology
Meningoencephalitis - therapy
Naegleria fowleri - isolation & purification
Parasitic diseases
Prevention
River water
Statistics
Swimming
Texas - epidemiology
Water Microbiology
title Primary Amebic Meningoencephalitis — Arizona, Florida, and Texas, 2007
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